Protein Alignment slim and KLHDC3

DIOPT Version :9

• Sequence 1: NP_523782.1
• Gene: slim / 37121
• FlyBaseID: FBgn0261477
• Length: 609
• Species: Drosophila melanogaster
• Sequence 2: XP_024302088.1
• Gene: KLHDC3 / 116138
• HGNCID: 20704
• Length: 395
• Species: Homo sapiens
• Alignment Length: 438
• Identity: 86/438 - (19%)
• Similarity: 135/438 - (30%)
• Gaps: 170/438 - (38%)

  Fly   153 LSKSVLNVFLSSDK---QQSQMAGQIPMYAFQPLRLVKCQYRDKHIPGGFPLARSGHRIIASNSH 214
            ||::|..|.|...|   .:|.:.||.|:                     .|..|.||..:..:..
Human    58 LSRAVPTVSLRWTKLPPVKSAIRGQAPV---------------------VPYMRYGHSTVLIDDT 101

  Fly   215 LYSLGGYNPRSAMSASRHGRCLLFQELWSYNFATRTWRLELNAGNAANMPVELASNALTIHNNVL 279
            :...||.|       ...|.|   ..|::::..|..|
Human   102 VLLWGGRN-------DTEGAC---NVLYAFDVNTHKW---------------------------- 128

  Fly   280 ISHGGTGYPFGVSCSNDCYVYRTASAGATPGVDRLQVKGDLPTAQYGPGIVIHKHFLYTIGGTTG 344
                                       .||     :|.|.:|.|:.|....:....:|..|   |
Human   129 ---------------------------FTP-----RVSGTVPGARDGHSACVLGKIMYIFG---G 158

  Fly   345 FD-----YTCDVYRLDLRTGIWENVYISRPEMRDDPEGRYR--HEVVYDGKHIFVLGG-----GT 397
            ::     ::.|:::||..|..|..:.     .:..| .|:|  |.....|.|::|.||     |.
Human   159 YEQQADCFSNDIHKLDTSTMTWTLIC-----TKGSP-ARWRDFHSATMLGSHMYVFGGRADRFGP 217

  Fly   398 SHSVYDL--QRIPAYNLEANCW-DYFET--YPDQRAADADDGNRGYPKPRKCFSCVQHQSSTGDI 457
            .||..::  .||..::.....| |...|  .|:.|.:.:..|..|
Human   218 FHSNNEIYCNRIRVFDTRTEAWLDCPPTPVLPEGRRSHSAFGYNG-------------------- 262

  Fly   458 EAFITGGLQGDFSTYFSDIWKLNLRTKHWYRIETAILPRPLYFHSAAHSDNGCMYV------FGG 516
            |.:|.||.....:.:|.|:||.|..:..|.:||      |............|..|      |||
Human   263 ELYIFGGYNARLNRHFHDLWKFNPVSFTWKKIE------PKGKGPCPRRRQCCCIVGDKIVLFGG 321

  Fly   517 ------------IEYIDKEMRRRNDLYKMWMTVPKLSEMCWDAITYYN 552
                        .:.||     .:||:.:..: |.|..:|..|:..||
Human   322 TSPSPEEGLGDEFDLID-----HSDLHILDFS-PSLKTLCKLAVIQYN 363

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
slim	NP_523782.1	KELCH repeat	203..263	CDD:276965	11/59 (19%)
		KELCH repeat	267..321	CDD:276965	4/53 (8%)
		KELCH repeat	324..364	CDD:276965	9/44 (20%)
		Kelch_1	325..372	CDD:279660	9/51 (18%)
		Kelch_4	441..492	CDD:290154	12/50 (24%)
		KELCH repeat	442..495	CDD:276965	12/52 (23%)
KLHDC3	XP_024302088.1	PLN02193	63..>331	CDD:330882	73/393 (19%)
		KELCH repeat	90..135	CDD:276965	14/114 (12%)
		KELCH repeat	141..186	CDD:276965	9/52 (17%)
		KELCH repeat	193..249	CDD:276965	15/55 (27%)
		KELCH repeat	252..296	CDD:276965	15/69 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910