Protein Alignment IVD and Arc42

DIOPT Version :10

• Sequence 1: XP_016877638.1
• Gene: IVD / 3712
• HGNCID: 6186
• Length: 516
• Species: Homo sapiens
• Sequence 2: NP_650840.1
• Gene: Arc42 / 42364
• FlyBaseID: FBgn0038742
• Length: 405
• Species: Drosophila melanogaster
• Alignment Length: 372
• Identity: 129/372 - (34%)
• Similarity: 197/372 - (52%)
• Gaps: 33/372 - (8%)

Human    41 AINGLSEEQRQLRQTMAKFLQEHLAPKAQEIDRSNEFKNLRVSWEVRAVGGSQGVGLSCTAAWKS 105
            :::.|||..:.|:::...|....|:..|.:.||.:.:...::
  Fly    23 SLSALSETHQMLQKSCRDFANNELSGNAAKFDREHLYPEKQI----------------------- 64

Human   106 SHSFLEFWKQLGNLGVLGITAPVQYGGSGLGYLEHVLVMEEISRASGAVGLSYGAHSNLCINQLV 170
                    :|:|.|||:.:..|.:.||:||.|:.:.:.||||||...:.|:....:::|.:..|:
  Fly    65 --------RQMGELGVMAVAIPEELGGTGLDYVAYAIAMEEISRGCASAGVIMSVNNSLYLGPLL 121

Human   171 RNGNEAQKEKYLPKLISGEYIGALAMSEPNAGSDVVSMKLKAEKKGNHYILNGNKFWITNGPDAD 235
            ..||:|||:.|:....:||.:|..|:|||..|||..:....|..||:|::|||.|.||||..:|:
  Fly   122 SFGNDAQKKDYITPFTTGERVGCFALSEPGNGSDAGAASTIATDKGDHFVLNGTKAWITNAFEAE 186

Human   236 VLIVYAKTDLAAVPASRGITAFIVEKGMPGFSTSKKLDKLGMRGSNTCELIFEDCKIPAANILGH 300
            ..||:|.|:...  ..:||:||||.|...|||..||.||||:|||:||:||||||.:|..|:||.
  Fly   187 AAIVFATTNKQL--KHKGISAFIVPKATKGFSLGKKEDKLGIRGSSTCQLIFEDCVVPKENMLGE 249

Human   301 ENKGVYVLMSGLDLERLVLAGGPLGLMQAVLDHTIPYLHVREAFGQKIGHFQLMQGKMADMYTRL 365
            ...|..:.|..||..|:.:||..||:.||.|:..:.|...|:|||:.|...|.:|.|:|||...:
  Fly   250 PGFGFKIAMQTLDAGRIGIAGQALGIGQAALELAVDYAQKRQAFGKPIAKLQSIQQKIADMSLAM 314

Human   366 MACRQYVYNVAKACDEGHCTAKDCAGVILYSAECATQVALDGIQCFG 412
            .:.|...:..|...|:.....|:.|...|.::|.||..:...||..|
  Fly   315 ESARLLTWRAAWLKDQKQPYTKEAAMAKLAASEAATLCSHQCIQILG 361

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
IVD	XP_016877638.1	IVD	44..412	CDD:173845	128/367 (35%)
Arc42	NP_650840.1	SCAD_SBCAD	29..401	CDD:173847	127/366 (35%)