DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment IVD and CG3902

DIOPT Version :9

Sequence 1:	XP_016877638.1	Gene:	IVD / 3712	HGNCID:	6186	Length:	516	Species:	Homo sapiens
Sequence 2:	NP_649069.2	Gene:	CG3902 / 40059	FlyBaseID:	FBgn0036824	Length:	414	Species:	Drosophila melanogaster

Alignment Length:	445	Identity:	140/445 - (31%)
Similarity:	218/445 - (48%)	Gaps:	78/445 - (17%)

- Green bases have known domain annotations that are detailed below.

Human     2 AEMATATRLLGWRVASWRLRPPLAGFVSQRAHSLLPVDDAINGLSEEQRQLRQTMAKFLQEHLAP 66
            |.|::||.|           ||...|                 |:::::.:::|:||..||.:.|
  Fly    22 AAMSSATGL-----------PPPLTF-----------------LTDDEKMMKETVAKLAQEQIQP 58

Human    67 KAQEIDRSNEFKNLRVSWEVRAVGGSQGVGLSCTAAWKSSHSFLEFWKQLGNLGVLGITAPVQYG 131
            ..:::|..::|....|                               |.:...|::||....:.|
  Fly    59 LVKKMDFEHKFDPSVV-------------------------------KAVFENGLMGIEIDTELG 92

Human   132 GSGLGYLEHVLVMEEISRASGAVGLSYGAHSNLCINQLVRNGNEAQKEKYLPKLISGEYIGALAM 196
            |||..::.:::|:||:|:...||......|:.|..:.:::.||..||.|||||| :.||.|:.|:
  Fly    93 GSGCNFMTNIVVVEELSKIDPAVAAFVDIHNTLVNSLMIKFGNAEQKAKYLPKL-AQEYAGSFAL 156

Human   197 SEPNAGSDVVSMKLKAEKKGNHYILNGNKFWITNGPDADVLIVYAKTDLAAVPAS--RGITAFIV 259
            :||.||||..|:|..|:|.|:||::||:|.||:|...|.|.:::|.    |.|..  ||||.|||
  Fly   157 TEPGAGSDAFSLKTVAKKDGSHYVINGSKMWISNSDVAGVFLIFAN----AKPEDGYRGITTFIV 217

Human   260 EKGMPGFSTSKKLDKLGMRGSNTCELIFEDCKIPAANILGHENKGVYVLMSGLDLERLVLAGGPL 324
            ::..||...:|..||||:|.|.||:|.|::.::|..||||....|.......|:..|:.:|...:
  Fly   218 DRETPGLIVNKPEDKLGIRASGTCQLTFDNVRVPEENILGTFGHGYKYAAGFLNEGRIGIAAQMV 282

Human   325 GLMQAVLDHTIPYLHVREAFGQKIGHFQLMQGKMADMYTRLMACRQYVYNVAKACDEGHCTAKDC 389
            ||.|...|.|||||..|:.||..|.:||.||.::|.:.|.:.|.|...||.|:..::|....|:.
  Fly   283 GLAQGTFDATIPYLLERKQFGDAIYNFQSMQHQIATVATEIEAARLMTYNAARLQEQGVPFQKEA 347

Human   390 AGVILYSAECATQVALDGIQCFGQT-FSAQHPPGR-----------EGETRGQTS 432
            |....|::|.|.:.|:..:...|.. |:...|..:           ||.|..|.|
  Fly   348 AMAKYYASEVAQRAAIKCVDWMGGVGFTRDFPQEKYYRDVKIGAIYEGTTNMQLS 402

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
IVD	XP_016877638.1	None
CG3902	NP_649069.2	CaiA	37..414	CDD:224871	132/402 (33%)
CG3902	NP_649069.2	SCAD_SBCAD	39..410	CDD:173847	131/400 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1960
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D589058at2759
OrthoFinder	1	1.000	-	-		FOG0000508
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.820