DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment PIG-O and AT5G17250

DIOPT Version :9

Sequence 1:	NP_611332.1	Gene:	PIG-O / 37118	FlyBaseID:	FBgn0034346	Length:	1077	Species:	Drosophila melanogaster
Sequence 2:	NP_001318581.1	Gene:	AT5G17250 / 831589	AraportID:	AT5G17250	Length:	946	Species:	Arabidopsis thaliana

Alignment Length:	1152	Identity:	310/1152 - (26%)
Similarity:	488/1152 - (42%)	Gaps:	307/1152 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 TYL--FVLIWLAFLI--SSGVMLFSRGFLLARVSKTETSTCRRLSTNPNAEYVLTDEVVNEIFKD 64
            |||  ..|..|.||:  :..:::|:|||||.|......|||..:|.:|    .|.....|.  ..
plant     3 TYLKNKKLTALGFLLIHAIAILIFTRGFLLTRTELPFHSTCSDVSLSP----CLASPRSNH--DS 61

  Fly    65 VNASSNLCLPQ------KSKVIVLVVDALKYEFGLYRANATDPLPYENKLVVLQELLQQNPDHAR 123
            .:..||...|:      ..:||::|:|||:.:|....|...:|.|:.:||.:||.|...|...|:
plant    62 SSGQSNQTQPKCWTKPVVDRVIIIVLDALRIDFVAPSAFFPEPKPWMDKLTILQTLAFANDSSAK 126

  Fly   124 LMRFRADPPTTTLQRLKGLTTGSLPTFIDIGSNFASPEINEDNIIDQIVKNDLPVVFLGDSTWTD 188
            :.:..||||||:||||||||||.||||||||::|.:|.|.|||.|:|:|.|...:|.:||.|||.
plant   127 IFKAFADPPTTSLQRLKGLTTGGLPTFIDIGNSFGAPAIVEDNFINQLVLNGKRLVMMGDDTWTQ 191

  Fly   189 LYPHRFKRSYSYPSFDIFDLDSVDNEILKHLPKELESKDWQVLVAHFLGVDHCGHKHGPMHEEMA 253
            |:|::|::||.:|||::.|||:|||..::||...|...||.||:||||||||.||..|.....|.
plant   192 LFPNQFQKSYPFPSFNVKDLDTVDNGCIEHLFPTLFKDDWDVLIAHFLGVDHAGHIFGVDSSPMI 256

  Fly   254 RKLGEMNEVIRSVVAAMDN---------DTTLLVMGDHGMTASGDHGGDTDDETNALLFAYS-KQ 308
            .||.:.|.|:..|:..:::         :|.|:||||||.|.:|||||.|.:|....:||.| |:
plant   257 NKLEQYNSVLEKVINILESQAGPGGLHENTMLIVMGDHGQTLNGDHGGGTAEEVETTMFAMSTKK 321

  Fly   309 HRFY-----------GNDSGSDS--EMLQQIDLVPTLATILGVPIPYSNLGLVNFNIVPDLRV-- 358
            |...           .|..|...  ..::|:|...||:.:||:..|:.::|.||    |:|..
plant   322 HTTLVPPEFDTSSCKQNKDGKQMCISYIEQLDFAATLSALLGISFPFGSIGHVN----PELYALG 382

  Fly   359 --------PHLNKFQT-LLLHSWQ---------NAQQIYRYFFQYALENKRTFNVEQMDHLETEF 405
                    ..|..|.| ...:.|.         ||.|:.||...|:..:...|:.:.|..:..
plant   383 SSSWNLDKSDLGNFGTQSAANEWMKHYVDVLCVNAWQVKRYIDVYSNSSVVGFSSDDMSRISD-- 445

  Fly   406 ILLTHRVQTVYNEVAFKSFVRDLNTNLRDILGTCREIWVRFDPTQMSQGLLFTFLPLFFIFLVVN 470
             |.:...|...|.|......|:.:....||....:|        |:::     :|..|...:.:.
plant   446 -LYSAAEQNWSNSVKHILMDRNGDDGSTDISALLKE--------QIAE-----YLNFFSSVVELA 496

  Fly   471 NSRPADFPHIFKAKEVFYVYLINLAAGVFGYRYFKTFSFKTEEQGVIFFTAISSAVILAFHTLRH 535
            .|:..:|               ||...:.|:             |::..:.|.. .:..||..:.
plant   497 RSKWTEF---------------NLNLMITGF-------------GILVISLILQ-FLAVFHGDKS 532

  Fly   536 WTSIATNWSAVKRFGHMPTRLLLFGSMAVFFSNSFVIQEAKILSYLLA-AAILLLSHELLRLSAR 599
            :.  ..:|.:.   |...|..::......|.|||::::|.|:.::||| ..::.|.:.::|.:.|
plant   533 YA--VGSWLST---GAAFTLFIVTIRACSFLSNSYILEEGKVANFLLATTGLIKLRYSVMRKTMR 592

  Fly   600 LDFRTKFKASQFLRSTALRLILASVLAICLIRFAYTLFRCREEQGNCSDFVNTGGA---GFSLKK 661
            .:      |..||   |:..:|...:.|.|.:.|.|           |.|:::..:   |.:...
plant   593 KE------AFMFL---AMVFVLRVSIDIGLTKQAAT-----------SQFMSSSPSWMLGIAPDH 637

  Fly   662 PGTGKTY------ILAVVVL--VVYTTLTRLYLRSCGNLTGNLPNVLLARYGPTVASICAGGHIL 718
            |..  ||      ||:||:|  |:|..:.:            .||..:.:| .||.|:.:...|.
plant   638 PAL--TYAIEIAPILSVVILICVLYVAIAK------------APNEGVWKY-VTVGSMVSYFFIA 687

  Fly   719 LANSSIKHIQRTHIDAMALV----------IYGLLLVQIIVLSWAPLMTFVLPPRSSHTVTINGN 773
            |..:|...|  ..:|.:..|          :|.:.|||:.:|:.|
plant   688 LLWASESKI--FGLDQLLQVTGGRNRIPQTVYVIGLVQLCLLASA-------------------- 730

  Fly   774 ESIVPEIFRKMKRMYEGDDDERRSHIPVVYGLATVYSSIVIAF----GVFLALVMIVLLEPRASI 834
                        ||:..:.|:..:...|  .|.:..||.:|..    |..||||.:|
plant   731 ------------RMFCTEKDKNWAIRTV--ALVSACSSPIILLSGKQGSMLALVYLV-------- 773

  Fly   835 GLVVCVAVGAILLSVHSILRYRTATSFES--------CVQPTFTALVGWFLLAHFCFFATSHQTT 891
                   .|..::.:..:.| ||.:..:|        ||       |.|.||:...|||:.|...
plant   774 -------AGYCIMRLEGVER-RTKSDGQSKFSKLNPLCV-------VQWSLLSICMFFASGHWCA 823

  Fly   892 LSQIEWRAAFVGRTTGIGQSNLVSGALVILNTFCGPIFFFCMYSLLSTETF------SLFALFPN 950
            ...:.:.||||    |..:..|:..|:                 ||:.|||      |:|.| |.
plant   824 FDGLRYGAAFV----GFDEFVLIRQAI-----------------LLTIETFGFSIILSVFGL-PL 866

  Fly   951 LI----RSCRSGGKVDASTSMSDLANEAVGFDMTRGELSLYEYEDVFLGTGFKLATQFFMLQGLK 1011
            ||    ::.::.|:                   .|.:|             |::...|.::....
plant   867 LIPFHSQTPQAHGE-------------------KRHQL-------------FQMYMLFGVISATT 899

  Fly  1012 IFCAMLACTIHCRHLMVWKIFAPRFIYEALATFVS--LPALIVGYLL 1056
            :...:|..||..||||||.:|||:|:::.:...::  |..|...|.|
plant   900 VTATILCVTIQRRHLMVWGLFAPKFVFDVVDLILTDLLICLASAYYL 946

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PIG-O	NP_611332.1	GPI_EPT_3	74..349	CDD:293747	127/303 (42%)
AT5G17250	NP_001318581.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	180	1.000	Domainoid score	I1049
eggNOG	1	0.900	-	-		E1_COG1524
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	300	1.000	Inparanoid score	I784
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D848878at2759
OrthoFinder	1	1.000	-	-		FOG0004973
OrthoInspector	1	1.000	-	-		oto3231
orthoMCL	1	0.900	-	-		OOG6_102855
Panther	1	1.100	-	-	LDO	PTHR23071
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3507
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.830