Protein Alignment PIG-O and ENPP5

DIOPT Version :9

• Sequence 1: NP_611332.1
• Gene: PIG-O / 37118
• FlyBaseID: FBgn0034346
• Length: 1077
• Species: Drosophila melanogaster
• Sequence 2: NP_001277001.1
• Gene: ENPP5 / 59084
• HGNCID: 13717
• Length: 477
• Species: Homo sapiens
• Alignment Length: 508
• Identity: 103/508 - (20%)
• Similarity: 187/508 - (36%)
• Gaps: 141/508 - (27%)

  Fly    57 VVNEIFKDVNASSNLCL-PQKSKVIVLVVDALKYEFGLYRANATDPLPYEN---------KLVVL 111
            :|:.|...::.|:...| |.:.||:::..|..:::: ||:.    |.|:.:         |.|..
Human     7 LVSFILAALSLSTTFSLQPDQQKVLLVSFDGFRWDY-LYKV----PTPHFHYIMKYGVHVKQVTN 66

  Fly   112 QELLQQNPDHARLMRFRADPPTTTLQRLKGLTTGSLPTFIDIGSNFASPEINEDNIIDQIVKNDL 176
            ..:.:..|:|..|:       |.......|:....:  |..|.:.  |..::..||.|.....:.
Human    67 VFITKTYPNHYTLV-------TGLFAENHGIVANDM--FDPIRNK--SFSLDHMNIYDSKFWEEA 120

  Fly   177 PVVFL---------GDSTW--TDLYPH-RFKRSYSYPSFDIFDLDSVDNEILKHL-------PKE 222
            ..:::         |.:.|  ||:..| ||...|...:..:    |.::.:.|.:       |..
Human   121 TPIWITNQRAGHTSGAAMWPGTDVKIHKRFPTHYMPYNESV----SFEDRVAKIIEWFTSKEPIN 181

  Fly   223 LESKDWQVL--VAHFLGVDHCGHKHGPMHEEMARKLGEMNEVIRSVVAAMDNDTTLLVMGDHGMT 285
            |....|:..  :.|.||.|  ....||:..::.:|||.:.::::.  |.:.|...|::..|||||
Human   182 LGLLYWEDPDDMGHHLGPD--SPLMGPVISDIDKKLGYLIQMLKK--AKLWNTLNLIITSDHGMT 242

  Fly   286 ASGDHGGDTDDETNALLFAYSKQHRFYGNDSGSDSEMLQQIDLVPTLATIL-----------GVP 339
                               ...:.|....|...|.:....||..| :|.||           .:.
Human   243 -------------------QCSEERLIELDQYLDKDHYTLIDQSP-VAAILPKEGKFDEVYEALT 287

  Fly   340 IPYSNLGL-------------VNFNIVPDLRVP----HL--NKFQTLLL--HSWQNA-QQIYRYF 382
            ..:.||.:             .|..|.|.:.|.    |:  ||....||  |.:.|| ..::..|
Human   288 HAHPNLTVYKKEDVPERWHYKYNSRIQPIIAVADEGWHILQNKSDDFLLGNHGYDNALADMHPIF 352

  Fly   383 FQYALENKRTFNVEQMDHLETEFILLTHRVQTVYNEVAFK---SFVRDLNTNLRDILGTCREIWV 444
            ..:....::.|:.|.|:..:. :.||.|    :.|..|..   ||     .|::|:|.:.....|
Human   353 LAHGPAFRKNFSKEAMNSTDL-YPLLCH----LLNITAMPHNGSF-----WNVQDLLNSAMPRVV 407

  Fly   445 RFDPTQMSQGLLFTFLPLFFIFLVVNNSRPADFPHIFKAKEVFYVYLINLAAG 497
            .:  ||.:             .|:..:.:||::.     :|..|.|.|.::.|
Human   408 PY--TQST-------------ILLPGSVKPAEYD-----QEGSYPYFIGVSLG 440

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PIG-O	NP_611332.1	GPI_EPT_3	74..349	CDD:293747	62/328 (19%)
ENPP5	NP_001277001.1	Phosphodiest	30..342	CDD:307681	70/355 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1524
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900