Protein Alignment PIG-O and pign

DIOPT Version :9

• Sequence 1: NP_611332.1
• Gene: PIG-O / 37118
• FlyBaseID: FBgn0034346
• Length: 1077
• Species: Drosophila melanogaster
• Sequence 2: NP_001297009.1
• Gene: pign / 556797
• ZFINID: ZDB-GENE-080204-114
• Length: 932
• Species: Danio rerio
• Alignment Length: 1083
• Identity: 205/1083 - (18%)
• Similarity: 347/1083 - (32%)
• Gaps: 384/1083 - (35%)

  Fly    74 PQKSKVIVLVVDALKYEFGLYRA--NATDPLPYENKLVVLQELLQQNPDHARLMRFRADPPTTTL 136
            |...::::.|.|.|:.: .|::.  :.|...||...  |::|.......|.|:       ||.:.
Zfish    43 PPAKRLVLFVADGLRAD-SLFKPDDSGTSRAPYLRS--VIEEGGTWGVSHTRV-------PTESR 97

  Fly   137 QRLKGLTTGSLPTFIDIGSNFASPEINEDNIIDQI------VKNDLPVVF----LGDSTWTDLYP 191
            .....|..|.......:...:....:..|::.::.      ...|:..:|    .||..:|..||
Zfish    98 PGHVALIAGFYEDVSAVAKGWKENPVEFDSVFNESRYTWCWGSPDILPMFAKGATGDHVYTHTYP 162

  Fly   192 HRFKRSYSYPSFDIFDLD-------------SVDNE-ILKHLPKELESKDWQVLVAHFLGVDHCG 242
               .....:.|.|...||             :..|| :||.|.:|     ..|...|.||:|..|
Zfish   163 ---PEREDFASTDASRLDTWVFDEVKDFLTAAKSNETLLKKLHEE-----QNVFFLHLLGIDTNG 219

  Fly   243 HKHGPMHEEMARKLGEMNEVIRSVVAAMDN------DTTLLVMGDHGMTASGDHGGDTDDETNAL 301
            |.|.||.:|....:|.::..:..:|..||:      .|..:...|||||..|.||.....||...
Zfish   220 HAHRPMSKECLENIGLVDAGVADIVTVMDDFYGHDGKTAYVFTSDHGMTNWGSHGAGHPSETLTP 284

  Fly   302 LFAY------------SKQHRFYGNDSGSDSEM---LQQIDLVPTLATILGVPIPYSNLGLVNFN 351
            |..:            .|....|..:.|.:|..   :.|.|:.|.:::::|:|.|.:::|:
Zfish   285 LVVWGAGVQKAQWETSQKYEDNYLKEWGLESYRRVDVNQADIAPLMSSLIGIPFPLNSVGV---- 345

  Fly   352 IVPDLRVPHLNKFQTLLLHS-WQNAQQIYRYFFQYALENKRTFNVEQMDHLETEFILLTHRVQTV 415
                |.:.:||..|.....| :.||.||...|.....:.|.|    .:..|.|.:..||...|.
Zfish   346 ----LPLSYLNNSQHFKAESMYANAIQILEQFRVKLAQKKET----TISFLFTPYQPLTDSKQV- 401

  Fly   416 YNEVAFKSFVRDLNTNLRDIL--GTCREIWVRFDPTQMSQGLLFTFLPLFFIFLVVNNSRPADFP 478
                   .|:|    ..||::  |       |||..
Zfish   402 -------DFIR----QARDLIQKG-------RFDEA----------------------------- 419

  Fly   479 HIFKAKEVFYVYLINLAAGVFGYRYFKTFSFKTEEQGVIFFTAISSAVILAFHTLRHWTSIA--- 540
             |...|::       :|..:.|..|:.|:.       .:|   :.|:|:|.|   ..|||..
Zfish   420 -IVYCKDL-------IAQAMEGLSYYHTYD-------RLF---LGSSVVLGF---IGWTSYVVLY 463

  Fly   541 ------------TNWSAVKRFGHMPTRLLLFG------SMAVFFSNSFVIQEAKILSYLLAAAIL 587
                        ||.|.|..      |||.:|      .||:|    .::|.:....|:.:...:
Zfish   464 ILKTHASLRKPPTNTSMVTE------RLLGWGFLCVGLLMALF----LLVQSSPWSYYIYSLMPV 518

  Fly   588 LLSHELLRLSARLDFRTKFKASQFLRSTALR------LILASVLAICLIRFAYTLFRCREEQGNC 646
            .:.:.:|:     :|:|.....:.:.|..|.      :::|..:.:.::.|.|..
Zfish   519 AVWYAVLK-----EFKTLVGLVRSIPSLPLTKCFGYFVLVAFGIELLVMSFFYRA---------- 568

  Fly   647 SDFVNTG---------GAGFSLKKPGTGKTYILAVVVLVVYTTLTRLYLRSCGNLTGNLPNVLLA 702
              .::.|         .:||..|......::.|:.:.|.|:..|.         :.|..||:...
Zfish   569 --MLSLGLVVLALWPVVSGFYTKAKFKSLSWTLSCLSLAVFPLLP---------VVGREPNINYV 622

  Fly   703 RYGPTVASICAGGHILLANSSIKHIQRTHIDAMALVIYGLLLVQIIVLSW--APLMTFVLPPRSS 765
                    |.|||.||..:||                       .:..||  :|||
Zfish   623 --------ISAGGLILFNSSS-----------------------FLWSSWRDSPLM--------- 647

  Fly   766 HTVTINGNESIVPEIFRKMKRMYEGDDDERRSHIPVVYGLATVYSSIVIAFGVFLALVMIVLLEP 830
                            |:.::::                   ::..:.:|...:
Zfish   648 ----------------RRDRQLF-------------------IFQMVQVALCAY----------- 666

  Fly   831 RASIGLVVCVAVGAILLSVHSILRYRTATSFESCVQPTFTALVGWFLLAHFCFFATSHQTTLSQI 895
                          .|.|.||.|:.:...       |.|..||.|..|      .:|....|
Zfish   667 --------------TLTSTHSSLQLKQGL-------PIFNQLVSWSTL------VSSFLIPL--- 701

  Fly   896 EWRAAFVGRTTGIGQSNLVSGALVILNTFCGPIFFFCMYSLLSTETFSLFALFPNLI-------- 952
                        :..:.|....|.||.:..      |:|.||||...:||.|..:.:
Zfish   702 ------------LSSTRLFHRLLSILMSLT------CVYLLLSTGHEALFPLMLSWLMLAWIHIE 748

  Fly   953 --RSCRSGGKVDASTSMSDLANEAVGFDMTR-GELSLYEYEDVFLGTGFKLATQFFMLQGLKIFC 1014
              ...|.|.......|..|.|.   ..|:|: .:|.|.:....:... |.:...||....:....
Zfish   749 QEAMSRQGSSNRNELSCIDFAE---NIDITKVRQLRLDDIRKSYFFV-FFIIIAFFGCGNIASIN 809

  Fly  1015 AMLACTIHC----------RHLMVWKIFAPRFIYEALATFVSL 1047
            :....:::|          ..|::||:..|..|  .:.||.|:
Zfish   810 SFDPASVYCFLTVFNPFIMGGLLMWKVLIPFVI--VMCTFESI 850

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PIG-O	NP_611332.1	GPI_EPT_3	74..349	CDD:293747	72/321 (22%)
pign	NP_001297009.1	Npp1	11..>282	CDD:224441	59/256 (23%)
		GPI_EPT_1	42..347	CDD:293744	72/329 (22%)
		PigN	433..885	CDD:282796	105/607 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910