Protein Alignment PIG-O and Pigg

DIOPT Version :9

• Sequence 1: NP_611332.1
• Gene: PIG-O / 37118
• FlyBaseID: FBgn0034346
• Length: 1077
• Species: Drosophila melanogaster
• Sequence 2: NP_001297618.1
• Gene: Pigg / 433931
• MGIID: 3576484
• Length: 983
• Species: Mus musculus
• Alignment Length: 1138
• Identity: 278/1138 - (24%)
• Similarity: 441/1138 - (38%)
• Gaps: 301/1138 - (26%)

  Fly    19 GVMLFSRGFLLARVSKTETSTCRRLSTNP--NAEYVLTDEVVNEIFKDVNAS-SNLCLPQKSKVI 80
            ||.:|.|||..|.|         |.|..|  :||....:.|..     |.:: :.|..|..|||:
Mouse    19 GVAIFIRGFFPAPV---------RSSARPEHDAETPAPEPVAG-----VRSNWTKLPPPLFSKVV 69

  Fly    81 VLVVDALKYEFGLYRANATDPLPYENKLVVLQELLQQNPDHARLMRFRADPPTTTLQRLKGLTTG 145
            ::::|||:.:| ::.:.....:||...||      ::...|:.:.  .|.|||.|:.|:|.|.||
Mouse    70 IVLIDALRDDF-VFGSKGVKYMPYTTYLV------EKGASHSFVA--EAKPPTVTMPRIKALMTG 125

  Fly   146 SLPTFIDIGSNFASPEINEDNIIDQIVKNDLPVVFLGDSTWTDLYPHRFKRSYSYPSFDIFDLDS 210
            |||.|:|:..|..||.:.|||::.|.......::|.||.||..|:|..|.......||.:.|...
Mouse   126 SLPGFVDVIRNLNSPVLLEDNVLRQAKAAGKRIIFYGDETWVKLFPKHFVEYDGTTSFFVSDYIE 190

  Fly   211 VDNEILKHLPKELESKDWQVLVAHFLGVDHCGHKHGPMHEEMARKLGEMNEVIRSV---VAAMDN 272
            ||..:.:||.|.|:..||.||:.|:||:||.||..||....:..||.||:.|:..:   :.:.|.
Mouse   191 VDKNVTRHLDKVLKRGDWDVLILHYLGLDHIGHISGPNSPLIGHKLSEMDSVLMKIHTSLLSKDR 255

  Fly   273 DT---TLLVM-GDHGMTASGDHGGDTDDETNALLFAYSKQHRFYGNDSGSDSEMLQQIDLVPTLA 333
            :|   :|||: |||||:.:|.||..:.:|.:..|...|........|. ...:.:||.||..|||
Mouse   256 ETLLPSLLVLCGDHGMSETGSHGASSTEEVSTPLLLISSAFERKPGDI-RHPKHVQQTDLAATLA 319

  Fly   334 TILGVPIPYSNLGLVNFNIV------PDLRVPHLNKFQ-TLLLHSWQNAQQIYRY-----FFQYA 386
            ..||:|||..::|.:.|.::      ..||..|||..| :.||.     :.:..|     |.|:.
Mouse   320 IGLGLPIPKDSVGSLLFPVIEGKPMREQLRFLHLNTLQLSKLLQ-----ENVPSYEKDPGFEQFK 379

  Fly   387 LENKRTFNVEQMDHLETEF--ILLTHRVQTVYNEV-AFKSFVRDLNTNLRDILGTCREIWVRFDP 448
            :..|...|..:: |||...  |||....:.:.:.: |.|:....|:|.:           .::|.
Mouse   380 MAEKLHGNWVKL-HLEENHSDILLGLGTKVLRHYLGALKTLSLSLSTQV-----------AQYDM 432

  Fly   449 TQMSQGLLFTFLPLFFIFLVVNNSRPADFPHIFKAKEVFYVYLINLAAGVFGYRYFKTFS----- 508
            ..|:.|.|.. |.:..:||:       ..||:...|....|.|::....:..|..|...|
Mouse   433 YSMAVGTLIV-LEVLALFLL-------STPHVLCRKAELDVPLLSPVFSLLFYLVFLVLSAIHVL 489

  Fly   509 --FKTEEQ-----------GVI------FFTAISSAVI--LAFHTL--RHWTSIATNWSAVKRFG 550
              ..:|..           |.:      .|.||.||:|  :...||  ::....::.||.|
Mouse   490 VCTSSESSCYLCSLSWLAVGAVMLLVSALFCAILSALIRMVIDSTLLKKNAADASSGWSEV---- 550

  Fly   551 HMPTRLLLFGSMAVFFS---NSFVIQEAKILSYLLAAAILLLSHELLRLSARLDFRTKFKASQFL 612
               ..|||.|::....|   :|||.:|.:...:|:....|.||.|..|             |.||
Mouse   551 ---NLLLLLGTVGHVLSLGASSFVEEEHQTWYFLINTLCLALSQETCR-------------SYFL 599

  Fly   613 RSTALRLILASVLAICLIRFAYTLFRCREEQGNCSDFVNTGGAG---FSLKKPGTGKTY-ILAVV 673
            .........:.|...|:     .|..|..:.....:...:|.||   ..|:..|:.|.: :||..
Mouse   600 GDECEPQRHSHVEQQCV-----NLLACPLQDSTSYNTPESGTAGKRVSLLEAQGSCKWWTVLASP 659

  Fly   674 VLVVYTTLTRLYLRSCGNLTGNLPNVLLARYGPTVASICAGGHILLANSSIKHIQRTHIDAMALV 738
            .||:   |....|||. |.||     :...:.|..:      |.|  .||...:|.:.:.|::||
Mouse   660 WLVL---LCCRLLRSL-NQTG-----VQGAHRPDFS------HWL--TSSDHKVQLSGLAALSLV 707

  Fly   739 IYGLL------LVQIIVLSWAPLMTFV---------LPPRSSHTVTINGNESIVPEIFRK----- 783
            :..:|      ||..:.|:...|..|.         .|.:|.       |:.|...|...
Mouse   708 VIFMLVQRRCSLVSKVALALGLLGVFCYRAAIGIVQFPWQSD-------NKGISKGIIEARFVYV 765

  Fly   784 --MKRMYEGDDDERRSHIPVVYGLATVYSSIVIAFGVFLALVMIVLLEPRASIGLVVCVAVGAIL 846
              :..::.|..|..::.:     :||.:.:..:.           |.|..:  |||:   :.|:|
Mouse   766 FVLGILFTGTKDLLKAQV-----IATDFKTKTVG-----------LWEMHS--GLVL---LAALL 809

  Fly   847 LSVHSILRYRTATSFESCVQPTFTALVG---------------WFLLAHFCFFATSHQTTLSQIE 896
            |..|::    ...:|...:|...|..:.               ||..|.|.|...|:  .::.|:
Mouse   810 LRPHNL----PVLAFSLLIQTVMTKFIWKPLRHDAAEITVMHYWFGQAFFYFQGNSN--NIATID 868

  Fly   897 WRAAFVGRTTGIGQSNLVSGALVILNTFCGPIFF--FCMYSLLSTETFSLFALFPNLIRSCRSGG 959
            ..|.|||..|   ...:.:..|.:..|:.||:.:  ..:|.|.|....|.      |.|||
Mouse   869 ISAGFVGLDT---YMEVPATFLTVFGTYVGPVLWASHLVYFLSSEGNNSA------LSRSC---- 920

  Fly   960 KVDASTSMSDLANEAVGFDMTRGELSLYEYEDVFLGTGFKLATQFFMLQGLKIFCAMLACTIHCR 1024
                                                                 ||..|.|::...
Mouse   921 -----------------------------------------------------FCYALICSVPVA 932

  Fly  1025 -----------HLMVWKIFAPRFIYEALATFVS 1046
                       ||.:|.:|:|:.:||.:...::
Mouse   933 TYIVLVTSLRYHLFIWSVFSPKLLYEGMHLLIT 965

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PIG-O	NP_611332.1	GPI_EPT_3	74..349	CDD:293747	100/281 (36%)
Pigg	NP_001297618.1	GPI_EPT_2	62..335	CDD:293748	100/282 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1524
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D313125at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820