Protein Alignment PIG-O and CG5342

DIOPT Version :10

• Sequence 1: NP_611332.1
• Gene: PIG-O / 37118
• FlyBaseID: FBgn0034346
• Length: 1077
• Species: Drosophila melanogaster
• Sequence 2: NP_650088.2
• Gene: CG5342 / 41389
• FlyBaseID: FBgn0037916
• Length: 837
• Species: Drosophila melanogaster
• Alignment Length: 1064
• Identity: 208/1064 - (19%)
• Similarity: 338/1064 - (31%)
• Gaps: 434/1064 - (40%)

  Fly     1 MNLTYLFVLIWLAFLISSGVMLFSRGFLLARVSKTETSTCRRLSTNPNAEYVLTDEVVNEIFKDV 65
            ::.|..|||..| .|:.:.|:::.|                  ||.|.:   |..:.|..:.:.
  Fly     2 LDSTRSFVLFQL-LLLFAVVLIYLR------------------STYPGS---LEPQEVEHLKEP- 43

  Fly    66 NASSNLCLPQKSKVIVLVVDALKYEFGLYRANATDPLPYENKLVVLQELLQQNPDHARLMRFRAD 130
                    |...:::|||.|.|..:  .:.||....:|...:|.:.|.|:
  Fly    44 --------PPADRLVVLVRDGLSAQ--SFLANRCTNVPLLRELFLHQGLV--------------- 83

  Fly   131 PPTTTLQRLKGLTTGSLPTFIDIGSNFASPEINEDNIIDQIVKNDLPVVFLGDSTWTDLYPHRFK 195
                .:.|.:.:|..|:..:|.:.|.|     |||  ...:.:.     :||.....|....|.|
  Fly    84 ----GISRPETITYHSISPYISLFSGF-----NED--AASVARG-----WLGTPASIDSIFDRCK 132

  Fly   196 RSYSYPSFDIFDLDSVDNEILKHLPK-----EL--------------ESKDWQV-LVAHFLG--- 237
            ||:::.:          .|::...||     ||              |.:|:.. .|..|||
  Fly   133 RSFAWTT----------TELISRFPKIERPRELSFETYGEGVTKSCSEMEDFVCRSVQRFLGGGS 187

  Fly   238 ---VDHCG-----HKHG--PMHEEMARKLGEMNEVIRSVVAAM-DNDTTLLVMGDHGMTASGDHG 291
               ::..|     |..|  |..|.:.|....:..|.:|..... |..|..|...:.|
  Fly   188 RLLLNTTGVIFFIHMTGVEPSCESLQRIQENVWNVYKSFEKTFPDQRTAYLFTSNLG-------- 244

  Fly   292 GDTDDETNA----------LLFAYSKQH-------RFYGNDSG--SDSEMLQQIDLVPTLATILG 337
               |.:|.:          .|:.....|       .|..|::|  ....:|....|...::.:||
  Fly   245 ---DPQTKSEYSLAVESPFFLWGSGVNHIKSMPGRSFMANEAGLRLPLHVLNTPHLTALMSALLG 306

  Fly   338 VPIP-YSN----LGLVNFNIVPDLRVPHLNKFQTLLLHSWQNAQQIYRYFFQYALENKRT----F 393
            ||.| ||.    .|::|.::..:.....:|..|.|     ..|:::..      |..||.    .
  Fly   307 VPPPVYSRGMLPKGMLNASLRYEANAMLINAKQLL-----AQARRLRE------LHPKRMPAFWL 360

  Fly   394 NVEQMDHLETEFILLTHRVQTVYNEVAFKSFVRDLNTNLRDILGTCREIWVRFDPTQMSQGLLFT 458
            :.:.||:...|.:.|.       .:..|::.: |.:.|
  Fly   361 SFQMMDNFVKESLALK-------KQRRFRALL-DYSCN--------------------------- 390

  Fly   459 FLPLFFIFLVVNNSRPADFPHIFKAKEVFYVYLINLAAGVFGYRYFKTFSFKTEEQGVIFFTAIS 523
            ::|:                 :.|..:.|..|          ||:             :..||:|
  Fly   391 YMPV-----------------LIKGMDYFKDY----------YRH-------------VSITAVS 415

  Fly   524 SAVILAFHTLR-HWT-------------SIATNWSAVKRFGHMPTRLLLFGSMAVFFSNSFVIQE 574
            .|.|...:.|| |.|             .|::......|..|.    ||.|.:.:      ::..
  Fly   416 FAGIAWIYCLRCHLTVGKKCRNLIEIQEVISSKRLVYARGFHR----LLTGVLVI------IMML 470

  Fly   575 AKILSYLLAAAILLLSHELLRLSAR-LDFRTKFKASQFLRSTALRLILA-------SVLAICLIR 631
            .:|  .|:..||||:.....|.:.: |..|.|....:.|.||||..::.       .:||:..:.
  Fly   471 ERI--PLVVQAILLIPSLYWRTTLKILGERPKMVCRKSLMSTALLALICFGGFFRRYILAVGYLG 533

  Fly   632 FA------------------------YTLFRCREEQGNCSDFVNTGGAGFSLKKPGTGKTYILAV 672
            ||                        .|:.....|...||             :||       |:
  Fly   534 FASYNNREAFKRRGHQFYLWLLLLLGLTVVSALPESLGCS-------------QPG-------AL 578

  Fly   673 VVLVVYTTLTRLYLRSCG---NL---TGNLPNVLLARYGPTVASICAGGHILLANSSIKHIQRTH 731
            :..:..|.|..|   :||   ||   ..|:| ||||    .:..|..|.|
  Fly   579 MFSIFLTVLRPL---ACGVYLNLLTWLSNIP-VLLA----ALEYILIGWH--------------- 620

  Fly   732 IDAMALVIYGLLLVQIIVLSWAPLMTFVLPPRSS--------------HTVTINGNESIVPEIF- 781
                ..::|        ::||..|...||..|.:              :|:|....||:|.::.
  Fly   621 ----PWIMY--------LVSWIYLGFLVLWQRRNLQASEVFFFDLSTLYTLTCTSYESVVIQMLA 673

  Fly   782 --------RKMKRMYEGDDDERRSHIPVVYGLATVYSSIVI----AFGVFL-------------- 820
                    .|:|| .|....:..:|..:||   :.||..:|    ||..||
  Fly   674 MELQLALRMKLKR-NESIGPKTAAHYILVY---SWYSLFIIGSFPAFDDFLDILHETCFGYSPLT 734

  Fly   821 -ALVMIV-LLEPRASIGLVVCVAVGAILLSVHSILRYRTATSFESCVQPTFTAL----------- 872
             .|||:: |:.|..   ||:|:..|          .|::..|:|   |..|..|
  Fly   735 YGLVMVLKLILPWL---LVLCIMAG----------NYKSLASYE---QQIFVRLLLMNSAMSLVL 783

  Fly   873 ------VG-W-FLLAHFCFFATSH 888
                  || | .:|:.|..||..|
  Fly   784 LHGITNVGPWRDILSRFAEFAVVH 807

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PIG-O	NP_611332.1	GPI_EPT_3	74..349	CDD:293747	68/332 (20%)
CG5342	NP_650088.2	GPI_EPT_1	43..318	CDD:293744	67/337 (20%)
		PigN	397..781	CDD:461508	103/493 (21%)