Protein Alignment PIG-O and Pign

DIOPT Version :9

• Sequence 1: NP_611332.1
• Gene: PIG-O / 37118
• FlyBaseID: FBgn0034346
• Length: 1077
• Species: Drosophila melanogaster
• Sequence 2: NP_038812.2
• Gene: Pign / 27392
• MGIID: 1351629
• Length: 931
• Species: Mus musculus
• Alignment Length: 1096
• Identity: 202/1096 - (18%)
• Similarity: 361/1096 - (32%)
• Gaps: 381/1096 - (34%)

  Fly    74 PQKSKVIVLVVDALK----YEF---GLYRANATDPLPYENKLVVLQELLQQNPDHARLMRFRADP 131
            |...::::.|.|.|:    ||.   |..||      |:...:::.:.  .....|.|:
Mouse    41 PPAKRLVLFVADGLRADTLYELDEDGNSRA------PFIRNVIMHEG--SWGVSHTRV------- 90

  Fly   132 PTTTLQRLKGLTTGSLPTFIDIGSNFASPEINEDNIIDQIVKNDLPVVFLGDSTWT----DLYP- 191
            ||.:......|..|.......:...:....:..|::.::           ...||:    |:.|
Mouse    91 PTESRPGHVALIAGFYEDVSAVAKGWKENPVEFDSLFNE-----------SKYTWSWGSPDILPM 144

  Fly   192 --------HRFKRSYSYPS----FDIFDLDSVDNEILKHLPKELE------------SKDWQVLV 232
                    |.:  :|||.:    |...|...:|..:...:....:            :::..|..
Mouse   145 FAKGASGDHVY--TYSYDAQREDFGAHDATKLDTWVFDKVKDFFDAARNNQSLFTKVNEEKVVFF 207

  Fly   233 AHFLGVDHCGHKHGPMHEEMARKLGEMNEVIRSVVAAM------DNDTTLLVMGDHGMTASGDHG 291
            .|.||:|..||.|.|...|....:.::::.::.:|:..      |..|..:...|||||..|.||
Mouse   208 LHLLGIDTNGHAHRPSSREYKDNIKKVDDGVKEIVSIFKHFYGDDGKTAFIFTSDHGMTDWGSHG 272

  Fly   292 GDTDDETNALLFAYSKQHRFYGNDSGS--DSEMLQ-------------QIDLVPTLATILGVPIP 341
            .....||......:....:|..|.|..  |.|.|:             |.|:.|.:|:::|||.|
Mouse   273 AGHPSETLTPFVTWGAGIKFPQNVSAQQYDDEFLKEWRLENWKRRDVNQADIAPLMASLIGVPFP 337

  Fly   342 YSNLGLVNFNIVPDLRVPHLNKFQTLLLHS-WQNAQQIYRYFFQYALENKRTFNVEQMDHLETEF 405
            .:::|:        |.|.:||........| :.||.||...|.....:.|..    .:..|.|.|
Mouse   338 LNSVGI--------LPVGYLNNTGLFKAESMFTNAVQILEQFKVKMTQKKEA----TLPFLFTPF 390

  Fly   406 ILLTHRVQTVYNEVAFKSFVRDLNTNLRDILGTCREIWVRFDPTQMSQGLLFTFLPLFFIFLVVN 470
            .||:...|......| :|:::  .....:::..|.|:                      |.|.:
Mouse   391 KLLSDSQQLDILRKA-RSYIK--QEKFDEVVSLCEEL----------------------IDLAL- 429

  Fly   471 NSRPADFPHIFKAKEVFYVYL-INLAAGVFGYRYFKTFSFKTEEQGVIFFTAISSAVILAFHTLR 534
              |...:.|.:..     ::| ||:|.|..|:..:                  :|.:|:..|
Mouse   430 --RGLSYYHTYDR-----LFLGINVAVGFVGWMSY------------------TSLLIIKSH--- 466

  Fly   535 HWTSIATNWSAVKRFGHMPTRLLLFGSMA--VFFSNSFVIQEAKILSY---LLAAAI---LLLSH 591
              ::|.   ...::.|..|..|||:..:|  |..:...:||......|   ||...|   :|..|
Mouse   467 --SNIP---KGTRKEGKKPHCLLLYSFIATGVLVACFLMIQACPWTYYVYCLLPVPIWYAVLREH 526

  Fly   592 ELLRLSARLDFRTKFKASQFLRSTALRLILASVLAICLIRFAYTLFRCREEQGNCSDFVNTGGAG 656
            |:::  ..::....|..|.|:   |..|:....:.:.::.|.|.             ::.|.|
Mouse   527 EVIQ--DLVESLLTFPRSHFV---AYLLVFTLGIEVLVLSFFYR-------------YMLTAG-- 571

  Fly   657 FSLKKPGTGKTYILAVVVLVVYTTLTRLYLRSCGNLTGNLPNVLLARYGPTVASICAGGHILLAN 721
                           ::|...:..||:|:.|:
Mouse   572 ---------------LIVFAGWPFLTQLWTRA--------------------------------- 588

  Fly   722 SSIKHIQRTHIDAMALVIYGLLLVQIIVLSWA--PLMTFVLPPRSSHTVTINGNESIVPEIFRKM 784
                                    :|..||||  .|:..|.|              ::|.:.||
Mouse   589 ------------------------KITFLSWAFFSLLLAVFP--------------LMPVVGRK- 614

  Fly   785 KRMYEGDDDERRSHIPVVYGLATVYSSIVIAFGVFLAL-----------VMIVLLEPRASIGLVV 838
                        .::.:|.|..  :..::::..|...|           ::::||:..:::
Mouse   615 ------------PNLSLVMGAG--FLVLLLSLAVVTTLGKRNIKLVKGELLVLLLQMLSTV---- 661

  Fly   839 CVAVGAILLSVHSILRYRTATSFESCVQPTFTALVGWFLLAHFCFFATSHQTTLSQIEWRAAFVG 903
             :::..:..:.||:|:....        |....:|.|..||..........|.|||
Mouse   662 -LSMYVVYSTHHSLLKKEGL--------PLMNQIVSWATLASSLVAPLLSSTALSQ--------- 708

  Fly   904 RTTGIGQSNLVSGALVILNTFCGPIFFFCMYSLLSTETFSLFALFPNLIR--------------- 953
                    .|.|..|.:::|          |.||||...:||.|..:.:.
Mouse   709 --------RLASILLSLMST----------YLLLSTGYEALFPLVLSCLMFVWIQVEQETLQQPG 755

  Fly   954 -SCRSGGKVDASTSMSDLA--NEAVGFDMTRGELSLYEYEDVFLGTG-------FKLATQFFMLQ 1008
             ||:........|..:|:|  .:....|:.|....::.....|.|||       |.||:.:..|.
Mouse   756 VSCKQKLTSIQFTCDTDIAQFRQLCPDDIRRAFFLVFFLLTAFFGTGNIASINSFDLASVYCFLT 820

  Fly  1009 GLKIFCAMLACTIHCRHLMVWKIFAPRFI-----YEA--LATFVSLPALIVGYLLV 1057
            ....|  |:..      ||:|||..| |:     :||  :.|.:|...|.:..|::
Mouse   821 VFSPF--MMGA------LMMWKILIP-FVLVMCAFEAVQITTQLSSKGLFLVVLII 867

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PIG-O	NP_611332.1	GPI_EPT_3	74..349	CDD:293747	66/331 (20%)
Pign	NP_038812.2	GPI_EPT_1	40..345	CDD:293744	66/339 (19%)
		PigN	431..884	CDD:368221	112/638 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1524
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810