Protein Alignment PIG-O and Enpp3

DIOPT Version :10

• Sequence 1: NP_611332.1
• Gene: PIG-O / 37118
• FlyBaseID: FBgn0034346
• Length: 1077
• Species: Drosophila melanogaster
• Sequence 2: NP_598766.2
• Gene: Enpp3 / 209558
• MGIID: 2143702
• Length: 874
• Species: Mus musculus
• Alignment Length: 233
• Identity: 54/233 - (23%)
• Similarity: 90/233 - (38%)
• Gaps: 45/233 - (19%)

  Fly    79 VIVLVVDALKYEFGLYRANATDPLPYENKLVVLQELLQQNPDHARLMRFRADPPTTTLQRLKGLT 143
            ||:..:|..:.|   |....:..||..||       |:....|::.|  ||..||.|......:.
Mouse   161 VILFSMDGFRAE---YLQTWSTLLPNINK-------LKTCGIHSKYM--RAMYPTKTFPNHYTIV 213

  Fly   144 TGSLPT---FIDIGSNFASPEINEDNIIDQIVKNDLPVVFLGDSTW-TDLYPHRFKRSYSYPSFD 204
            ||..|.   .||  :|.....:|::..:..:.|:: |..:.|...| |.:|.......|.:|..|
Mouse   214 TGLYPESHGIID--NNMYDVHLNKNFSLSSVEKSN-PAWWSGQPIWLTAMYQGLKAACYYWPGSD 275

  Fly   205 I-----FDL------DSVDNE-----ILK--HLPKELESKDWQVLVAHFLGVDHCGHKHGPMHEE 251
            :     |..      :||..|     :|:  .|||......:.:.|..   .|..||..||:...
Mouse   276 VAVNGSFPTIYRNYSNSVPYERRITTLLQWLDLPKADRPSFYTIYVEE---PDSAGHSSGPVSAG 337

  Fly   252 MARKLGEMNEVIRSVVAA-----MDNDTTLLVMGDHGM 284
            :.:.|..::.....::..     :.|...::|:.||||
Mouse   338 VIKALQSVDNAFGMLMEGLKQRNLHNCVNIIVLADHGM 375

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PIG-O	NP_611332.1	GPI_EPT_3	74..349	CDD:293747	54/233 (23%)
Enpp3	NP_598766.2	SO	50..93	CDD:197571
		Cell attachment site. /evidence=ECO:0000255	78..80
		SO	94..137	CDD:197571
		Phosphodiesterase. /evidence=ECO:0000250|UniProtKB:O14638	160..544		54/233 (23%)
		Phosphodiest	161..485	CDD:396300	54/233 (23%)
		Nuclease. /evidence=ECO:0000250|UniProtKB:O14638	581..874
		NUC	627..856	CDD:214683