Protein Alignment PIG-O and Enpp2

DIOPT Version :9

• Sequence 1: NP_611332.1
• Gene: PIG-O / 37118
• FlyBaseID: FBgn0034346
• Length: 1077
• Species: Drosophila melanogaster
• Sequence 2: XP_036015136.1
• Gene: Enpp2 / 18606
• MGIID: 1321390
• Length: 1001
• Species: Mus musculus
• Alignment Length: 698
• Identity: 121/698 - (17%)
• Similarity: 198/698 - (28%)
• Gaps: 316/698 - (45%)

  Fly    79 VIVLVVDALKYEFGLYRANATDPLPYENKLVVLQELLQQNPDHARLMRFRADP--PTTTLQRLKG 141
            :|:..||..:..:          :...:|::...|.|:....||..||    |  ||.|...|..
Mouse   227 LIIFSVDGFRASY----------MKKGSKVMPNIEKLRSCGTHAPYMR----PVYPTKTFPNLYT 277

  Fly   142 LTTGSLP-----------------TF--------------------------IDIGSNFASPEIN 163
            |.||..|                 ||                          :..|:.|.|..|.
Mouse   278 LATGLYPESHGIVGNSMYDPVFDATFHLRGREKFNHRWWGGQPLWITATKQGVRAGTFFWSVSIP 342

  Fly   164 EDNIIDQIVK------NDLPVVFLGDSTWTDLYPHRF------KRSYSYPSFDIFDLDSVDNEIL 216
            .:..|..|::      |:.|.|:...|...|...|::      :.||..|      |........
Mouse   343 HERRILTILQWLSLPDNERPSVYAFYSEQPDFSGHKYGPFGPEESSYGSP------LTPAKRPKR 401

  Fly   217 KHLPKELESKDWQVLVA-------------HFLGVDHCGHKHGPMHEEMARKLGEMNEVIRSVVA 268
            |..||..:.:.    ||             |:...........|: .|:.:.:|::.:.::.:
Mouse   402 KVAPKRRQERP----VAPPKKRRRKLHRMDHYTAETRQDKMTNPL-REIDKTVGQLMDGLKQL-- 459

  Fly   269 AMDNDTTLLVMGDHGM---TAS-----GDHGGDTDDET--------------NALLF-------- 303
            .:.....::.:|||||   |..     .::..:.||.|              |.|.:
Mouse   460 KLHRCVNVIFVGDHGMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRPKIPNNLKYDPKAIIAN 524

  Fly   304 -----------AYSKQHR----------------------------------------FYGNDSG 317
                       .|.|||.                                        |:..|.|
Mouse   525 LTCKKPDQHFKPYMKQHLPKRLHYANNRRIEDLHLLVERRWHVARKPLDVYKKPSGKCFFQGDHG 589

  Fly   318 SDSEMLQQ----IDLVPTLATILGVPIPYSNLGLVNFNIVPDL---------------------- 356
            .|:::...    :...||......|| |:.|:.|  :|::.||
Mouse   590 FDNKVNSMQTVFVGYGPTFKYRTKVP-PFENIEL--YNVMCDLLGLKPAPNNGTHGSLNHLLRTN 651

  Fly   357 ---------------------------------RVPHLNKFQTL--LLHSWQNAQQIYRYFFQYA 386
                                             :|...||.:.|  .||:..:.:.....|....
Mouse   652 TFRPTLPEEVSRPNYPGIMYLQSDFDLGCTCDDKVEPKNKLEELNKRLHTKGSTEAETGKFRGSK 716

  Fly   387 LENKRTF--NVE--QMDHL---------ETEFILLTHR-VQTVYNEVAFKSFVRDLNT------- 430
            .|||::.  |||  :..||         .|.:.:|.|. .::.|:|:    |:..|.|
Mouse   717 HENKKSLNGNVEPRKERHLLYGRPAVLYRTSYDILYHTDFESGYSEI----FLMPLWTSYTISKQ 777

  Fly   431 ----NLRDILGTCREIWVRFDP------------TQMSQGLLFTFLPLFF---------IFLVVN 470
                ::.:.|..|....||..|            .|||.|.||   |.:.         .|||.|
Mouse   778 AEVSSIPEHLTNCVRPDVRVSPGFSQNCLAYKNDKQMSYGFLF---PPYLSSSPEAKYDAFLVTN 839

  Fly   471 NSRPADFPHIFKAKEVFYVYL--------------INLAAG-VFGYRY 503
                  ...::.|.:..:.|.              :|:.:| :|.|.|
Mouse   840 ------MVPMYPAFKRVWTYFQRVLVKKYASERNGVNVISGPIFDYNY 881

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PIG-O	NP_611332.1	GPI_EPT_3	74..349	CDD:293747	72/424 (17%)
Enpp2	XP_036015136.1	SO	118..159	CDD:197571
		SO	160..203	CDD:197571
		Phosphodiest	227..591	CDD:396300	64/390 (16%)
		NUC	753..983	CDD:214683	29/142 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1524
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900