Protein Alignment PIG-O and pigg

DIOPT Version :9

• Sequence 1: NP_611332.1
• Gene: PIG-O / 37118
• FlyBaseID: FBgn0034346
• Length: 1077
• Species: Drosophila melanogaster
• Sequence 2: XP_005173129.1
• Gene: pigg / 100538291
• ZFINID: ZDB-GENE-141215-6
• Length: 972
• Species: Danio rerio
• Alignment Length: 1133
• Identity: 270/1133 - (23%)
• Similarity: 455/1133 - (40%)
• Gaps: 277/1133 - (24%)

  Fly     6 LFVLIWLAFLISSGVMLFSRGFLLARVSKTETSTCRRLSTNPNAEYVLTDEVVNE------IFKD 64
            :|.|:.|...|.| :.||.|||....| |:..|...:::..| ||....:..||.      :||
Zfish     7 VFALLCLILEIVS-IALFLRGFFPVPV-KSSFSAKSKVTDIP-AEPQTGNNAVNSSRAPALLFK- 67

  Fly    65 VNASSNLCLPQKSKVIVLVVDALKYEFGLYRANATDPLPYENKLVVLQELLQQNPDHARLMRFRA 129
                         :|:::::|||:.:| ::.:|....:||...:|      ::...|:.:.:.|
Zfish    68 -------------RVVIVLIDALREDF-VFSSNGRRFMPYTRHVV------EKGSSHSFIAKAR- 111

  Fly   130 DPPTTTLQRLKGLTTGSLPTFIDIGSNFASPEINEDNIIDQIVKNDLPVVFLGDSTWTDLYPHRF 194
             |||.|:.|:|.|||||:|.|||:..|..||.:.|||:|.|.......::|.||.||..|:|..|
Zfish   112 -PPTVTMPRIKALTTGSIPGFIDVVMNLNSPVLLEDNLIWQAKSAGKRIIFYGDDTWVRLFPKHF 175

  Fly   195 KRSYSYPSFDIFDLDSVDNEILKHLPKELESKDWQVLVAHFLGVDHCGHKHGPMHEEMARKLGEM 259
            .......||.:.|...|||.:.:||...|:..||.:|:.|:||:||.||..||....:..||.||
Zfish   176 MEQDGTTSFFVSDYTEVDNNVTRHLDSTLKRDDWDILILHYLGLDHIGHISGPHSSLIGPKLMEM 240

  Fly   260 NEVIRSVVAAM---DNDTT----LLVMGDHGMTASGDHGGDTDDETNALLFAYSKQHRFYGNDSG 317
            :::|:.:.|::   :::.|    |:|.|||||:.:|.|||.::.|.|..|...|...|   ...|
Zfish   241 DDIIKKIHASLISKESEGTLPNLLVVCGDHGMSETGSHGGSSEQEINTALVLISPAFR---RKVG 302

  Fly   318 SD-SEMLQQIDLVPTLATILGVPIPYSNLGLVNFNIVP----------DLRVPHLNKFQTLLLHS 371
            .: ..:::|:||.||||..||:||..:::|    .::|          .||:..:|..|  |...
Zfish   303 LERPAVVEQVDLAPTLALGLGLPISQNSVG----RLIPAVFEELSMREQLRMLQINGHQ--LSQL 361

  Fly   372 WQNAQQIYRYFFQYALENKRTFNVEQMDHLETEFILLTHRVQTVYNEVAFK------SFVRDLNT 430
            .|::..::     :..:....|.|.:..|.....:.:......|.:.:..|      ..::.:::
Zfish   362 LQDSNPVF-----HKEDGYEQFRVAEKAHGSWMKLYVDGNKSEVLSNMGKKVRKQYLDALKAMSS 421

  Fly   431 NLRDILGTCREIWVRFDPTQMSQGLLFTFLPLFFIFLVVNN--SRPA--DFPHIFKAKEV-FYV- 489
            .|...:|       ::|...|...:.|....||.:.|.:..  ||.|  |.|.......: ||:
Zfish   422 ALSKQMG-------KYDLYSMIIAMTFILQVLFLLLLAMPEALSRDAVVDVPLASSLLSLPFYLL 479

  Fly   490 --------YLINLAAGVFGYRYFKTFSFKTEEQGVIFFTAI--SSAVILAFHTLRHWTSIATNWS 544
                    .|:..:||  |..|..:..:      |:.|:.|  |||...|...:.......:|.:
Zfish   480 CLFGSALHVLVCTSAG--GPCYLCSLPW------VLVFSVILLSSAFTCALVGMAARRLPTSNKT 536

  Fly   545 AVKRFGHMPTR---LLLFGSMAVFF-----SNSFVIQEAKILSYLLAAAILLLSHELLRLSARLD 601
            ..|..|...:.   |||.|:  ||.     |:||:.:|.:...:||....|.:..::    .|..
Zfish   537 PTKSSGWALSELDALLLTGT--VFHTLSLGSSSFIEEEHQTWYFLLNTLCLAVFQDV----CRRY 595

  Fly   602 FRTKFKASQFLRSTALRLILASVLAICLIRFAYTLFRCREEQGNCSDFVNTGGAGFSLK-----K 661
            ||.:.:..:                             .|::|......:..|..||..     .
Zfish   596 FREQRQGGE-----------------------------EEDEGPLLPSASDAGLSFSPALELGVS 631

  Fly   662 PGTGKTYILAVVVLVVYTTLTRLYLRSCGNLTG----NLPNVLLARYGPTVASICAGGHILLANS 722
            .|:.|...|...:|    |||...|....|.||    :||:.               ||.|  ||
Zfish   632 AGSEKWLALGTPLL----TLTCCRLLRALNQTGVQWAHLPDF---------------GHWL--NS 675

  Fly   723 SIKHIQRTHIDAMALVIYGLLLVQ---------------IIVLSW-APLMTFVLP-PRSSHTVTI 770
            ....:..:.:.|::|::. |:|||               :.|.|: |.:...:.| |.||..|:.
Zfish   676 GDHKVFLSVLAAVSLLLI-LVLVQRHCSLVSKIALTLGLLGVYSYRAAVGNVLFPWPHSSRQVSK 739

  Fly   771 NGNESIVPEIFRKMKRMYEGDDDERRSHIP---------VVYGLATVYSSIVIAFGVFLALVMIV 826
            ...|:....:| .:..::.|..|..||.:.         ...||..|||.:|        |::.:
Zfish   740 GTVEARFVYVF-VLGILFTGVKDLLRSQVMSSAVDSGRLKSRGLWEVYSGVV--------LLVAL 795

  Fly   827 LLEPRASIGLVVCVAVGAILLS-VHSILRYRTATSFESCVQPTFTALVGWFLLAHFCFFATSHQT 890
            |........|..|:.|..|:.. :...|.|..|.:         |.:..||..|.|.|...|:
Zfish   796 LFRAHNLPTLACCLLVQTIMAQFIWKKLHYDAAQT---------TIMHYWFGQAFFYFQGNSN-- 849

  Fly   891 TLSQIEWRAAFVGRTTGIGQSNLVSGALVILNTFCGPIFFFC-MYSLLSTETFSLFALFPNLIRS 954
            .:..::....|||..:.:....::   |..|:|:.||:.:.| :...||::|
Zfish   850 NIGTVDISVGFVGLESYVEAPAII---LTALSTYAGPLLWACHLLCYLSSQT------------- 898

  Fly   955 CRSGGKVDASTSMSDLANEAVGFDMTRGELSLYEYEDVFLGTGFKLATQFFMLQGL-KIFCAMLA 1018
                                               :.|..|.|.. :..|.:|:.: .:|..:|.
Zfish   899 -----------------------------------DRVVNGLGHG-SYCFALLRSIPAVFYVVLV 927

  Fly  1019 CTIHCRHLMVWKIFAPRFIYEALATFVS 1046
            ..:. .||.:|.:|:|:.:|||:.|.::
Zfish   928 TALR-YHLFIWSVFSPKLLYEAMHTLIT 954

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PIG-O	NP_611332.1	GPI_EPT_3	74..349	CDD:293747	99/282 (35%)
pigg	XP_005173129.1	Npp1	28..>286	CDD:224441	91/282 (32%)
		GPI_EPT_2	66..335	CDD:293748	101/298 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1524
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D313125at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820