Protein Alignment CG5174 and TPD52L1

DIOPT Version :9

• Sequence 1: NP_001246407.1
• Gene: CG5174 / 37117
• FlyBaseID: FBgn0034345
• Length: 369
• Species: Drosophila melanogaster
• Sequence 2: NP_001305832.1
• Gene: TPD52L1 / 7164
• HGNCID: 12006
• Length: 209
• Species: Homo sapiens
• Alignment Length: 231
• Identity: 58/231 - (25%)
• Similarity: 104/231 - (45%)
• Gaps: 66/231 - (28%)

  Fly   157 SEP--ASPANSVASAEIAAEFAALSVEEKEQRRAEWSQELARVEEEINTLRTVLASKTRHASDLK 219
            :||  .:..::||||:.:   :.||.||||:.:|    ||.::|:||.|||.||::|.||..::|
Human    11 TEPLQGTDEDAVASADFS---SMLSEEEKEELKA----ELVQLEDEITTLRQVLSAKERHLVEIK 68

  Fly   220 RKLGITVWKEVTDDVNQGLKNLKESTVYQSVEQSVGTFTKTVYEAPLYQRTESVLKSTGEKTASV 284
            :|||:.:..|:..:.::...:::.:|.                    |::|...|...|:|..:.
Human    69 QKLGMNLMNELKQNFSKSWHDMQTTTA--------------------YKKTHETLSHAGQKATAA 113

  Fly   285 FGSITSGISSK------------------LSQMKNSESMRSIEASVGSAYENVKVSYEHNNFMCQ 331
            |.::.:.||.|                  :..|:||.:.:|.|..|.:...::|
Human   114 FSNVGTAISKKFGDMRSHSIGYSIRHSISMPAMRNSPTFKSFEERVETTVTSLK----------- 167

  Fly   332 SHATKVTSRSGSVSSFPDALDENNTSSGLNSPTDSL 367
               |||...:.:..||.:.|     ||..::...||
Human   168 ---TKVGGTNPNGGSFEEVL-----SSTAHASAQSL 195

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5174	NP_001246407.1	TPD52	158..314	CDD:282107	47/175 (27%)
TPD52L1	NP_001305832.1	TPD52	12..192	CDD:367870	56/225 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165146209
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4010
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	100	1.000	Inparanoid score	I5001
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1225782at2759
OrthoFinder	1	1.000	-	-		FOG0000981
OrthoInspector	1	1.000	-	-		otm41657
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19307
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4903
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	11	10.890