Protein Alignment CG5174 and TPD52

DIOPT Version :9

• Sequence 1: NP_001246407.1
• Gene: CG5174 / 37117
• FlyBaseID: FBgn0034345
• Length: 369
• Species: Drosophila melanogaster
• Sequence 2: NP_001374707.1
• Gene: TPD52 / 7163
• HGNCID: 12005
• Length: 261
• Species: Homo sapiens
• Alignment Length: 156
• Identity: 53/156 - (33%)
• Similarity: 86/156 - (55%)
• Gaps: 31/156 - (19%)

  Fly   170 EIAAEFAA---LSVEEKEQRRAEWSQELARVEEEINTLRTVLASKTRHASDLKRKLGITVWKEVT 231
            ::||..:|   ||.||:|:.|    :|||:|||||.||..|||:|.:|.:::||||||...:|:.
Human    20 DVAATISATETLSEEEQEELR----RELAKVEEEIQTLSQVLAAKEKHLAEIKRKLGINSLQELK 80

  Fly   232 DDVNQGLKNLKESTVYQSVEQSVGTFTKTVYEAPLYQRTESVLKSTGEKTASVFGSITSGISSKL 296
            .::.:|.:::..::.                    |::|...|...|:|.::.|.|:.|.|:.||
Human    81 QNIAKGWQDVTATSA--------------------YKKTSETLSQAGQKASAAFSSVGSVITKKL 125

  Fly   297 SQMKNSESMRSIEASVGSAYENVKVS 322
            ..:|||.:.:|.|..|    ||:|.|
Human   126 EDVKNSPTFKSFEEKV----ENLKGS 147

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5174	NP_001246407.1	TPD52	158..314	CDD:282107	49/146 (34%)
TPD52	NP_001374707.1	TPD52	12..145	CDD:398052	51/152 (34%)
		MRP-S35	148..252	CDD:402037	53/156 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165146212
Domainoid	1	1.000	54	1.000	Domainoid score	I11225
eggNOG	1	0.900	-	-		E1_KOG4010
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	100	1.000	Inparanoid score	I5001
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1225782at2759
OrthoFinder	1	1.000	-	-		FOG0000981
OrthoInspector	1	1.000	-	-		otm41657
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19307
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4903
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	12	11.890