DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5174 and Tpd52l2

DIOPT Version :9

Sequence 1:	NP_001246407.1	Gene:	CG5174 / 37117	FlyBaseID:	FBgn0034345	Length:	369	Species:	Drosophila melanogaster
Sequence 2:	XP_006500756.1	Gene:	Tpd52l2 / 66314	MGIID:	1913564	Length:	230	Species:	Mus musculus

Alignment Length:	238	Identity:	69/238 - (28%)
Similarity:	119/238 - (50%)	Gaps:	27/238 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   133 DNYKRFLNIGHRSRGTKFDNTANLSEPASPANSVASAEIAAEFAALSVEEKEQRRAEWSQELARV 197
            |:..:.:|:...::|...|...::  |..|  .|.......|  .|:..|:|:.||    |||:|
Mouse     2 DSASQDINLNSPNKGVLSDFMTDV--PVDP--GVVHRTPVVE--GLTEGEEEELRA----ELAKV 56

  Fly   198 EEEINTLRTVLASKTRHASDLKRKLGITVWKEVTDDVNQGLKNLKESTVYQSVEQSVGTFTKTVY 262
            ||||.|||.|||:|.||..:|||:||::...|:..::::...:::.||.|....:.:|.:.:.|.
Mouse    57 EEEIVTLRQVLAAKERHCGELKRRLGLSTLGELKQNLSRSWHDVQVSTAYVKTSEKLGEWNEKVT 121

  Fly   263 EAPLYQRTESVLKSTGEKTASVFGSITSGISSKLSQMKNSESMRSIEASVGSAYENVKVSYEHNN 327
            ::.||::|:..|...|:||::...::.|.||.||..|:    ...:..|..|:|     |..|
Mouse   122 QSDLYKKTQETLSQAGQKTSAALSTMGSAISRKLGDMR----AHPLSQSFSSSY-----SIRH-- 175

  Fly   328 FMCQSHATKVTSRSGSVSSFPDALD--ENNTSSGLNSPTDSLP 368
                |.:..|...|.:..||.|.:.  ::....|..:.:|:||
Mouse   176 ----SISMPVMRNSATFKSFEDRVGTIKSKVVGGRENGSDNLP 214

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5174	NP_001246407.1	TPD52	158..314	CDD:282107	51/155 (33%)
Tpd52l2	XP_006500756.1	TPD52	<55..221	CDD:367870	53/175 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836311
Domainoid	1	1.000	57	1.000	Domainoid score	I10835
eggNOG	1	0.900	-	-		E1_KOG4010
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	80	1.000	Inparanoid score	I5198
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000981
OrthoInspector	1	1.000	-	-		otm43702
orthoMCL	1	0.900	-	-		OOG6_107924
Panther	1	1.100	-	-	LDO	PTHR19307
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4903
SonicParanoid	1	1.000	-	-		X5007
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.780