DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5174 and tpd52l2a

DIOPT Version :9

Sequence 1:	NP_001246407.1	Gene:	CG5174 / 37117	FlyBaseID:	FBgn0034345	Length:	369	Species:	Drosophila melanogaster
Sequence 2:	XP_005167067.1	Gene:	tpd52l2a / 335107	ZFINID:	ZDB-GENE-030131-7047	Length:	219	Species:	Danio rerio

Alignment Length:	246	Identity:	67/246 - (27%)
Similarity:	105/246 - (42%)	Gaps:	72/246 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   160 ASPANSVASAEIAAEFA---ALSVEEKEQRRAEWSQELARVEEEINTLRTVLASKTRHASDLKRK 221
            :|...|..:|.|||...   .::.||.|    |...||.:||:||.|||.||.:|.|||::||.:
Zfish     3 SSEQGSSMNAGIAAGMTLPPGVTEEEAE----EMQMELIKVEDEIETLRQVLVAKERHAAELKHR 63

  Fly   222 LGITVWKEVTDDVNQGLKNLKESTVYQSVEQSVGTFTKTVYEAPL----------------YQRT 270
            |||:...|:..::.:|..:::.|..|....|::|...:.|..:.|                |:||
Zfish    64 LGISPLSEIKQNITKGWHDVQCSNAYMRTSQTLGDLNRRVTSSNLYLTASATLEDIGRSDAYKRT 128

  Fly   271 ESVLKSTGEKTASVFGSITSGISSKLSQ-----------------------MKNSESMRSIEASV 312
            :..|...|:.|::.|.|:.|.|.|:..:                       |:||.|.:|.|..|
Zfish   129 QETLSQAGQVTSAAFSSMGSAIRSRFGEMRALPYSDSGSNLSMRHSLSMPAMRNSPSFKSFEDKV 193

  Fly   313 GSAYENVKVSYEHNNFMCQSHATKVTSRSGSVSSFPDALDENNTSSGLNSP 363
                ||:|.              ||..|:...:      |.:.||:  |:|
Zfish   194 ----ENMKY--------------KVMGRANGEN------DHSPTSN--NAP 218

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5174	NP_001246407.1	TPD52	158..314	CDD:282107	56/195 (29%)
tpd52l2a	XP_005167067.1	TPD52	<36..218	CDD:282107	55/207 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170579786
Domainoid	1	1.000	61	1.000	Domainoid score	I10445
eggNOG	1	0.900	-	-		E1_KOG4010
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1225782at2759
OrthoFinder	1	1.000	-	-		FOG0000981
OrthoInspector	1	1.000	-	-		otm25094
orthoMCL	1	0.900	-	-		OOG6_107924
Panther	1	1.100	-	-	O	PTHR19307
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R17289
SonicParanoid	1	1.000	-	-		X5007
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	13	12.740