DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5174 and tpd52l2b

DIOPT Version :9

Sequence 1:	NP_001246407.1	Gene:	CG5174 / 37117	FlyBaseID:	FBgn0034345	Length:	369	Species:	Drosophila melanogaster
Sequence 2:	XP_021325415.1	Gene:	tpd52l2b / 322103	ZFINID:	ZDB-GENE-030131-822	Length:	245	Species:	Danio rerio

Alignment Length:	228	Identity:	61/228 - (26%)
Similarity:	107/228 - (46%)	Gaps:	52/228 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   133 DNYKRFLNIGHRSRGTKFDNTANLSEPASPANSVASAEIAAEFAALSVEEKEQRRAEWSQELARV 197
            |...:.:|:....:|...|:.::|.|....| :|:...:.   ..|:.||.|:.|.    ||.:|
Zfish     2 DTANQDINLNSPHKGLGSDSISDLPEERGAA-AVSPGTLP---PGLTEEEAEELRL----ELTKV 58

  Fly   198 EEEINTLRTVLASKTRHASDLKRKLGITVWKEVTDDVNQGLKNLKESTVYQSVEQSVGTFTKTV- 261
            ||||||||.||::|.||||:||||||::...|...::.:..::::.|..|.::.:.:|.:.:.|
Zfish    59 EEEINTLRQVLSAKERHASELKRKLGLSPLTEFKQNITKSWQDVQTSNAYVTMSEKLGQWNEKVK 123

  Fly   262 ---------------YEAPLYQRTESVLKSTGEKTASVFGSITSGISSKLSQ------------- 298
                           ..:.:|::|:..|...|:||::...::.:.||.||..
Zfish   124 GCDIYLSASSTLDDITSSEVYKKTQETLSQAGQKTSAALSTVGTAISRKLGDMRALPFSNSFGSN 188

  Fly   299 -----------MKNSESMRSIEASVGSAYENVK 320
                       |:||.:.:|.|..||    |:|
Zfish   189 YSIRHSISMPTMRNSPTFKSFEDKVG----NIK 217

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5174	NP_001246407.1	TPD52	158..314	CDD:282107	53/195 (27%)
tpd52l2b	XP_021325415.1	TPD52	<56..233	CDD:309362	46/166 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170579785
Domainoid	1	1.000	61	1.000	Domainoid score	I10445
eggNOG	1	0.900	-	-		E1_KOG4010
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1225782at2759
OrthoFinder	1	1.000	-	-		FOG0000981
OrthoInspector	1	1.000	-	-		otm25094
orthoMCL	1	0.900	-	-		OOG6_107924
Panther	1	1.100	-	-	LDO	PTHR19307
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4903
SonicParanoid	1	1.000	-	-		X5007
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	14	13.740