DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5174 and Tpd52l3

DIOPT Version :9

Sequence 1:	NP_001246407.1	Gene:	CG5174 / 37117	FlyBaseID:	FBgn0034345	Length:	369	Species:	Drosophila melanogaster
Sequence 2:	XP_006231322.1	Gene:	Tpd52l3 / 293894	RGDID:	1309391	Length:	243	Species:	Rattus norvegicus

Alignment Length:	219	Identity:	58/219 - (26%)
Similarity:	92/219 - (42%)	Gaps:	40/219 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   155 NLSEPASPANSVASAEIAA---EFAALSVEE-KEQRRAEWSQELARVEEEINTLRTVLASKTRHA 215
            :|:|..|.:.|.|..|.:|   ||...|..: .|..:.|...||.::||||.:||.:||:|.:..
  Rat    47 SLNEDLSLSVSDAMTETSASTNEFHLASEPDLTEAEQMELRSELTKLEEEILSLRDLLAAKEKRC 111

  Fly   216 SDLKRKLGITVWKEVTDDVNQGLKNLKESTVYQSVEQSVGTFTKTVYEAPLYQRTESVLKSTGEK 280
            .:||||||......:..::::...:::.|..|..                             :|
  Rat   112 GELKRKLGCVALVGLRQNLSKSWHDVQASNTYMK-----------------------------QK 147

  Fly   281 TASVFGSITSGISSKLSQMKNSESMRSIEASVGSAYENVKVSYEHNNFMCQSHATKVTSRSGSVS 345
            |::...|:.|.|..||..||.|.:.:|:|..||:....|....|..:.:..|.|:.....|...|
  Rat   148 TSTALASMGSAICRKLGDMKKSSTFKSLEELVGTVKSRVAGGRELGSGLLPSPASGSDPHSVLGS 212

  Fly   346 SFPDALDENNTSSGLNSPTDSLPK 369
            .:       .|.|||:....||.|
  Rat   213 GY-------ETVSGLDDQLFSLLK 229

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5174	NP_001246407.1	TPD52	158..314	CDD:282107	43/159 (27%)
Tpd52l3	XP_006231322.1	TPD52	58..205	CDD:282107	45/175 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166339977
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4010
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	91	1.000	Inparanoid score	I5011
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1225782at2759
OrthoFinder	1	1.000	-	-		FOG0000981
OrthoInspector	1	1.000	-	-		otm45779
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19307
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	10	9.860