Protein Alignment Dp1 and hdlbpa

DIOPT Version :10

• Sequence 1: NP_523781.2
• Gene: Dp1 / 37116
• FlyBaseID: FBgn0027835
• Length: 1301
• Species: Drosophila melanogaster
• Sequence 2: NP_958882.2
• Gene: hdlbpa / 794178
• ZFINID: ZDB-GENE-030131-2032
• Length: 1272
• Species: Danio rerio
• Alignment Length: 1316
• Identity: 591/1316 - (44%)
• Similarity: 868/1316 - (65%)
• Gaps: 62/1316 - (4%)

  Fly     1 MQAAAVMEETNNATTIEQQPIALINGQEQVANEQQPSS-PTSVATPTSTTSGGTGNATPAFSYDD 64
            |.:.||:.:    .:..:....|:..|.:.|....||| ....:.||               |.|
Zfish     1 MSSVAVLTQ----ESFNEHRSGLLPEQVKAAAGGDPSSVEDDDSLPT---------------YKD 46

  Fly    65 LFPALPAN---TSAQSQSGASGSTLARVTSSQKTHIVHVPCKERKSTESEKFGEGESKRICQQIT 126
            .||.||..   ...|....|..:.:..:.||..|.:.|||.:|||..:..:||||:..::|..|.
Zfish    47 AFPPLPEKPLPEGVQETENAWTTKIKPLKSSIITQVFHVPLEERKYKDMNQFGEGDQAKVCLDIM 111

  Fly   127 KETGAQIEIVSGKNQSLTFLIKGKQSELLDARRKILMGFSTQASRQVTVPREHFRVILGKGGQRL 191
            .:|||.:|:...|:|.|:.::.||...::.||::|:....||||..|.:|:||.|.::||.|::|
Zfish   112 HKTGAHLELSMAKDQGLSIMVSGKYDAVMKARKEIVSRLQTQASATVAIPKEHHRFVIGKSGEKL 176

  Fly   192 REIERVTATRINIPSQSDESEFITIAGTKEGIAQAEQEIRQLSAEQYKKSSDRITVPKVYHPFIV 256
            :|:|..|||:|.||...|.|..|.|:|||||:.:|:.||..:||||.|::.:|:.:.||:||||.
Zfish   177 QELELKTATKIQIPRPDDPSNQIKISGTKEGLEKAKHEILLISAEQDKRAVERMNIDKVFHPFIT 241

  Fly   257 GPYSENLNKLQEETGARINVPPQQVQKDEIVISGEKDAVAAAKAKVEAIYKDMEKKCSTVSVEVA 321
            |.:.:.:..|.:||||||||||..|.|.||||:|||:.||.|..|::.:|::.:|..:|::|||.
Zfish   242 GAHGKLVGDLMQETGARINVPPPSVNKTEIVITGEKEQVALAMVKIKKLYEEKKKNATTIAVEVK 306

  Fly   322 KPKHRYVIGPKGSTIAEILQLTGVSVEMPPNDSPSETITLRGPQVALGNALTVVYQKSNSVKSVE 386
            |.:|:|||||||:|:.|||:.||||||:||.||.|||:.|||....||.|||.||.|:||.....
Zfish   307 KSQHKYVIGPKGNTLQEILERTGVSVEIPPLDSSSETVILRGEPARLGQALTEVYAKANSYTVSS 371

  Fly   387 INAAHWIHKYVIGRKGANMKQLEEDCPNVNVNCL--EDKIKLEGDPENVDRAVAYLSEIIKNYEE 449
            ::|..|:|:::||:||.|:.::.:..|.|::...  ||||.|||..::|......:..|:.:...
Zfish   372 VSAPSWLHRFIIGKKGQNLAKITQQMPKVHIEFTEGEDKITLEGPTKDVQIVQGQIEVIVTDLVS 436

  Fly   450 NFTFEVMTVNPSYYKHIIGKAGANVNRLKDELKVNINI-EEREGQNNIRIEGPKEGVRQAQLELQ 513
            ...:..::|:|.:::|:|||.|||:||:|:..||::.| .:.|..|.|||||..:||::|:.||.
Zfish   437 RMDYTEISVDPKFHRHLIGKGGANINRIKELHKVSVRIPPDNEKSNLIRIEGDPQGVQEAKKELL 501

  Fly   514 EKIDKLENEKSKDVIIDRRLHRSIIGAKGEKIREVKDRYRQVTITIPTPQENTDIVKLRGPKEDV 578
            |...::|||::||:||::|.||:|||.|||||:|::|::.:|.|..|.|.:.:|||:||||:.:|
Zfish   502 ELASRMENERTKDMIIEQRFHRAIIGQKGEKIKEIRDKFPEVIINFPDPAQKSDIVQLRGPRTEV 566

  Fly   579 DKCHKDLLKLVKEIQESSHIIEVPIFKQFHKFVIGKGGANIKKIRDETQTKIDLPAEGDTNEVIV 643
            :||.|.:.|:|.|:.|:|..:.|||||||||.:||||||||||||:||.||||||||...:|:||
Zfish   567 EKCSKFMQKMVAEMVENSFSVSVPIFKQFHKNIIGKGGANIKKIREETNTKIDLPAENSNSEMIV 631

  Fly   644 ITGKKENVLEAKERIQKIQNELSDIVTEEVQIPPKYYNSIIGTGGKLISSIMEECGGVSIKFPNS 708
            |||||.|...||.||..||.||::|...||.||.|.:||:||:.|:.:.|||||||||.|.||..
Zfish   632 ITGKKANCEAAKNRILAIQKELANITEVEVSIPSKLHNSLIGSKGRFVRSIMEECGGVHIHFPTE 696

  Fly   709 DSKSDKVTIRGPKDDVEKAKVQLLELANERQLASFTAEVRAKQQHHKFLIGKNGASIRKIRDATG 773
            .|..|.||||||.::|||||.|||.||.|:|..|.|.|:|||.::|||||||.|.:|||:||:||
Zfish   697 GSGIDAVTIRGPAEEVEKAKKQLLSLAEEKQTKSHTVELRAKPEYHKFLIGKGGGNIRKVRDSTG 761

  Fly   774 ARIIFPSNEDTDKEVITIIGKEESVKKAREQLEAIIKECDEVTEGEVSVDPKHHKHFVAKRGFIL 838
            ||||||:.||.|.|:||:||.||:|.:|:::|||:||..|.:.|..:.||||||:.|||:||.:|
Zfish   762 ARIIFPTAEDKDHELITVIGTEEAVAEAQKELEALIKSLDNIVEDFMIVDPKHHRFFVARRGQVL 826

  Fly   839 HRISEECGGVMISFPRVGINSDKVTIKGAKDCIEAARQRIEEIVADLEAQTTIEVVIPQRHHRTI 903
            ..|::|.|||::||||....|||||:||||||:|||::|:.|::.||:||.|:|.||||:.||:|
Zfish   827 RDIADEYGGVIVSFPRTAAQSDKVTLKGAKDCVEAAKKRMLEMIEDLDAQVTMECVIPQKFHRSI 891

  Fly   904 MGARGFKVQQVTFEFDVQIKFPDRDATEPVEGLTNGGSGENGGENEGQEGEQEVEKEAEQEPVRQ 968
            ||.:|.::||:|.:.:||||||||:..:..:....    |||      |...||::..:....::
Zfish   892 MGPKGSRIQQITKDHNVQIKFPDREEQQQADASVQ----ENG------EANGEVKEPVDPTAPKK 946

  Fly   969 CDVIRITGRIEKCEAAKQALLDLIPIEEELSVPFDLHRTIIGPRGANVRQFMSKHDVHVELPPSE 1033
            ||||.::||.|:||||.:||..|:|:...:.|||:|||.|||.:|:.:|:.|.:.:|::::|..|
Zfish   947 CDVIVLSGRKERCEAAVEALKALVPVTIAVEVPFELHRYIIGQKGSGIRKMMDEFEVNIQVPAHE 1011

  Fly  1034 LKSDVIKVCGTPARVAEAREALVKMIEDYEADRADRELRSFVLQVDVDTEFHSKLIGRHGAVINK 1098
            |:||:|.:.|..:.:..|:|.|::.:::.:|::.||.||||.|.:.|:.::|.|:|||.||:|:.
Zfish  1012 LQSDIISITGLASHLDRAKEGLLERVKELQAEQEDRALRSFKLTITVEPKYHPKIIGRKGAIISH 1076

  Fly  1099 LRADHDVIISLPKRDEPNDRIISITGYQANAEAARDAILEIVGDPETLHREVIEIDKRIHPHLIG 1163
            :|.||:|.|..|::::.|...|:||||:.||.||||||..||.:.|.:..|.|.:|.|:|..:||
Zfish  1077 IRHDHEVNIQFPEKNDENQDQITITGYEQNAIAARDAIQAIVDELEEMISEDITLDSRVHARIIG 1141

  Fly  1164 QRRRTIRKIIEDNKVNIKF----SADDDNPNSIFISGKIEDVENVKELLFGMAEDYERDYLDNVA 1224
            .|.:.||||:::.||:::|    :||   ||.:.::|:.|.|:...:.|..:.|:|..|.::|.|
Zfish  1142 ARGKGIRKIMDEFKVDVRFPQSGAAD---PNLVTVTGRPEHVDEAIDHLLNLEEEYMADVVENEA 1203

  Fly  1225 IAPPTIGAFLTGQGSGSDAAGASE-----NGFVIKDAPWEKQKQAKNLTAPNTQSQEDFPHFAAG 1284
            ..     |::  :.|||.|:...|     .|||:::|||    ...|..||:..|.|:||.|
Zfish  1204 KM-----AYM--KPSGSSASSMEEPRGPSKGFVVREAPW----ATGNEKAPDMSSSEEFPSF--- 1254

  Fly  1285 GAPVASTPITSVWGPK 1300
            |||||:....|.||||
Zfish  1255 GAPVAAAARASPWGPK 1270

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dp1	NP_523781.2	KH-I_Vigilin_rpt1	95..162	CDD:411833	24/66 (36%)
		KH-I_Vigilin_rpt2	165..239	CDD:411834	37/73 (51%)
		KH-I_Vigilin_rpt3	243..>290	CDD:411835	25/46 (54%)
		KH-I_Vigilin_rpt4	315..376	CDD:411836	38/60 (63%)
		KH-I_Vigilin_rpt5	382..449	CDD:411837	19/68 (28%)
		KH-I_Vigilin_rpt6	451..517	CDD:411804	28/66 (42%)
		KH-I_Vigilin_rpt7	522..588	CDD:411838	33/65 (51%)
		KH-I_Vigilin_rpt8	599..659	CDD:411839	43/59 (73%)
		KH-I_Vigilin_rpt9	668..737	CDD:411840	41/68 (60%)
		KH-I_Vigilin_rpt10	741..806	CDD:411841	39/64 (61%)
		KH-I_Vigilin_rpt11	817..882	CDD:411842	38/64 (59%)
		KH-I_Vigilin_rpt12	890..991	CDD:411843	42/100 (42%)
		KH-I_Vigilin_rpt13	993..1070	CDD:411844	26/76 (34%)
		KH-I_Vigilin_rpt14	1074..1144	CDD:411845	33/69 (48%)
		KH-I_Vigilin_rpt15	1147..1214	CDD:411846	23/70 (33%)
hdlbpa	NP_958882.2	None