DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dp1 and bicc1b

DIOPT Version :9

Sequence 1:	NP_001286573.1	Gene:	Dp1 / 37116	FlyBaseID:	FBgn0027835	Length:	1301	Species:	Drosophila melanogaster
Sequence 2:	XP_700087.4	Gene:	bicc1b / 571411	ZFINID:	ZDB-GENE-080522-3	Length:	850	Species:	Danio rerio

Alignment Length:	249	Identity:	66/249 - (26%)
Similarity:	106/249 - (42%)	Gaps:	56/249 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   608 HKFVIGKGGANIKKIRDETQTKIDLPAEGDTNEV-----IVITGKKENVLEAKERIQK-----IQ 662
            |..||||||.||||:.::|...|..|.....|:.     :.|.|:...|..|:.||::     :.
Zfish    22 HSHVIGKGGNNIKKVMEDTGCHIHFPDSNRNNQAEKSNQVSIAGQPGGVEAARARIRELLPLVLM 86

  Fly   663 NELSDIV-------TEEVQIPPKYYNSIIGTGGKLISSIMEECGGVSIKFPNSDSKSDKVTIRGP 720
            .||..||       :..:|...:.||  |....|..|.:....|                .:||.
Zfish    87 FELPVIVQLNPDPSSPAIQHISQTYN--ISVAFKQRSRLYGATG----------------VVRGS 133

  Fly   721 KDD---VEKAKVQLLE--LANERQLASFTAEVRAKQQHHKFLIGKNGASIRKIRDATGARIIFPS 780
            :::   |::....|||  ..|.....:.:.::....|||.|::|:||::|:.|...|||::.||.
Zfish   134 QNNAAAVKRGTAVLLEHLAGNLASAITISTQLDIAPQHHLFMMGRNGSNIKHIMQRTGAQVHFPD 198

  Fly   781 -NEDTDKEVITIIGKEESVKKAREQLEAI--------IKECDEVTEGEVSVDPK 825
             |....|..:.:.|..:||..||:.|...        |||       ::.|:|:
Zfish   199 PNCPQKKSTVYVQGTIDSVCLARQYLMGCLPLVLMFDIKE-------DIEVEPQ 245

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dp1	NP_001286573.1	vigilin_like_KH	170..231	CDD:239087
		vigilin_like_KH	242..>290	CDD:239087
		vigilin_like_KH	315..373	CDD:239087
		vigilin_like_KH	384..440	CDD:239087
		vigilin_like_KH	454..513	CDD:239087
		vigilin_like_KH	524..586	CDD:239087
		vigilin_like_KH	598..659	CDD:239087	20/55 (36%)
		vigilin_like_KH	670..732	CDD:239087	10/64 (16%)
		vigilin_like_KH	744..806	CDD:239087	21/62 (34%)
		vigilin_like_KH	817..879	CDD:239087	2/9 (22%)
		vigilin_like_KH	890..989	CDD:239087
		vigilin_like_KH	995..1055	CDD:239087
		vigilin_like_KH	1075..1137	CDD:239087
		vigilin_like_KH	1149..1208	CDD:239087
bicc1b	XP_700087.4	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910