Protein Alignment Dp1 and Hdlbpl1

DIOPT Version :10

• Sequence 1: NP_523781.2
• Gene: Dp1 / 37116
• FlyBaseID: FBgn0027835
• Length: 1301
• Species: Drosophila melanogaster
• Sequence 2: NP_001100436.1
• Gene: Hdlbpl1 / 302772
• RGDID: 1562485
• Length: 677
• Species: Rattus norvegicus
• Alignment Length: 698
• Identity: 222/698 - (31%)
• Similarity: 365/698 - (52%)
• Gaps: 56/698 - (8%)

  Fly   590 KEIQESSHIIEVPIFKQFHKFVIGKGGANIKKIRDETQTKIDLPAEGDTNEVIVITGKKENVLEA 654
            :.:|..||:..:                        ...|::.|:....:|..:...|.||....
  Rat    13 RSLQRESHVTNL------------------------NSRKVNFPSSSCNSENNISIRKPENREIC 53

  Fly   655 KERIQKIQNELSDIVTEEVQIPPKYYNSIIGTGGKLISSIMEECGGVSIKFPNSDSKSDKVTIRG 719
            ...|..|....:.....|:.|||..:.|:..:...||.||:||||.|.|.||:::....||.|.|
  Rat    54 HNWILSIPKNAAKDSEVEIPIPPSLHRSLTDSKKSLIGSIIEECGKVQIHFPSNNQGPQKVIISG 118

  Fly   720 PKDDVEKAKVQLLELANERQLASFTAEVRAKQQHHKFLIGKNGASIRKIRDATGARIIFPSNEDT 784
            ..|.|||||.:||:||.|.|..|::..:..|.::|:||:.|||.:::.|.:.||.|||||:.::.
  Rat   119 TTDIVEKAKKRLLQLAEEEQAKSYSVAIPVKSKYHQFLMSKNGGNLQSICEKTGVRIIFPTFKNK 183

  Fly   785 DKEVITIIGKEESVKKAREQLEAIIKECDEVTEGEVSVDPKHHKHFVAKRGFILHRISEECGGVM 849
            |:|.|||||.||:||..::.:|.::|:.::|.|..:.:.||.|.:||.:||.:|..|.:|.|||.
  Rat   184 DQESITIIGTEEAVKNVKKVVEVLLKDLEDVVEDNILISPKFHNYFVMQRGQLLREIIKEYGGVF 248

  Fly   850 ISFPRVGINSDKVTIKGAKDCIEAARQRIEEIVADLEAQTTIEVVIPQRHHRTIMGARGFKVQQV 914
            ::|...|..|.||||||||.|:|||::.|:.|...|.:|.|.:.|:|.:.|..|||....::||.
  Rat   249 VTFSYAGKQSTKVTIKGAKACVEAAKKHIQGIFDPLGSQVTAQCVVPPKFHPFIMGPICSRIQQT 313

  Fly   915 TFEFDVQIKFPDRDATEPVEGLTNGGSGENGGENEGQEGEQEVEKEAEQEPVRQCDVIRITGRIE 979
            ..|..|||||||   ||.....|:    ....|.|..:|.:.|.|.|...| ::.|....:|:.|
  Rat   314 ARECKVQIKFPD---TEKTTKKTH----PEVQEMEKDKGGKNVRKPASTSP-KKSDTTSTSGKTE 370

  Fly   980 KCEAAKQALLDLIPIEEELSVPFDLHRTIIGPRGANVRQFMSKHDVHVELPPSELKSDVIKVCGT 1044
            .|:.|.|||..|:|:..|:.|||.||..|||.||:.:|:.:...:||:::........:|.:.|.
  Rat   371 NCKEAAQALETLVPVTAEVQVPFHLHPYIIGHRGSGLRKLIKDFEVHIQVSQPGGNFHIISIMGL 435

  Fly  1045 PARVAEAREALVKMIEDYEADRADRELRSFVLQVDVDTEFHSKLIGRHGAVINKLRADHDVIISL 1109
            .|.|.:|:..|...::..:.:..|:.||||.....:|:::|||:.|..|.:|:::..::||.:..
  Rat   436 EANVEQAKTKLQNQVKALQMELDDQTLRSFRQTFRLDSKYHSKIFGNKGILISQICTEYDVTVHF 500

  Fly  1110 PKR--DEPNDRIISITGYQANAEAARDAILEIVGDPE-TLHREVIEIDKRIHPHLIGQRRRTIRK 1171
            .|:  :...|: |:|:|.::|...|||||:.::...| |:.|| |.::..:..::||...::|:|
  Rat   501 SKKGSNSTQDQ-ITISGSKSNILGARDAIMNMLRKIEKTVSRE-IPLNHHVCANIIGFGGKSIQK 563

  Fly  1172 IIEDNKVNIKFSADDDNPNS-IFISGKIEDVENVKELLFGMAEDYERDYLDNVAIAPPTIGAFLT 1235
            |:|...|:|:......:.|| |.:||...:|:...:.:..:    |:.:|......||:..   .
  Rat   564 IMEQYHVDIRVPPKGSHTNSTIIVSGSSANVQEAIDYILSL----EKHFLSVGKSDPPSDH---H 621

  Fly  1236 GQGSGSDAAGASENGFVIKDAPWEKQKQAKNLTA----PNTQSQEDFP 1279
            .:|...:.|..:...|       .|:...:|:.:    |:..:.||||
  Rat   622 KRGGVCNTAARTYKSF-------GKRNTLRNVKSTTHPPHLDNAEDFP 662

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dp1	NP_523781.2	KH-I_Vigilin_rpt1	95..162	CDD:411833
		KH-I_Vigilin_rpt2	165..239	CDD:411834
		KH-I_Vigilin_rpt3	243..>290	CDD:411835
		KH-I_Vigilin_rpt4	315..376	CDD:411836
		KH-I_Vigilin_rpt5	382..449	CDD:411837
		KH-I_Vigilin_rpt6	451..517	CDD:411804
		KH-I_Vigilin_rpt7	522..588	CDD:411838
		KH-I_Vigilin_rpt8	599..659	CDD:411839	6/59 (10%)
		KH-I_Vigilin_rpt9	668..737	CDD:411840	31/68 (46%)
		KH-I_Vigilin_rpt10	741..806	CDD:411841	27/64 (42%)
		KH-I_Vigilin_rpt11	817..882	CDD:411842	30/64 (47%)
		KH-I_Vigilin_rpt12	890..991	CDD:411843	35/100 (35%)
		KH-I_Vigilin_rpt13	993..1070	CDD:411844	22/76 (29%)
		KH-I_Vigilin_rpt14	1074..1144	CDD:411845	21/71 (30%)
		KH-I_Vigilin_rpt15	1147..1214	CDD:411846	17/67 (25%)
Hdlbpl1	NP_001100436.1	KH-I	69..136	CDD:469614	31/66 (47%)
		KH-I	140..196	CDD:469614	24/55 (44%)
		KH-I	216..280	CDD:469614	30/63 (48%)
		KH-I	289..382	CDD:469614	35/100 (35%)
		KH-I	384..459	CDD:469614	21/74 (28%)
		KH-I	465..537	CDD:469614	21/72 (29%)
		KH-I	539..605	CDD:469614	17/70 (24%)