Protein Alignment Dp1 and Gm382

DIOPT Version :10

• Sequence 1: NP_523781.2
• Gene: Dp1 / 37116
• FlyBaseID: FBgn0027835
• Length: 1301
• Species: Drosophila melanogaster
• Sequence 2: NP_001028413.2
• Gene: Gm382 / 211208
• MGIID: 2685228
• Length: 1250
• Species: Mus musculus
• Alignment Length: 1262
• Identity: 374/1262 - (29%)
• Similarity: 630/1262 - (49%)
• Gaps: 120/1262 - (9%)

  Fly    66 FPALPANTSAQSQSG--ASGSTLARVTSSQKTHIVHVPCKERKSTESEKFGEGESKRICQQITKE 128
            |...|..|:..|.|.  .:|..      |..|.|.||..:|.|..  .:||||...:....|.:.
Mouse    46 FSGNPEETAESSNSNIFKAGEI------SNLTRIFHVLLEEEKYL--TQFGEGTLAKFYAHIMEN 102

  Fly   129 TGAQIEIVSGKNQSLTFLIKGKQSELLDARRKILMGFSTQASRQVTVPREHFRVILGKGGQRLRE 193
            ||..:|....|:|.|...:.|....:.:|..:|......|......:.::.....|.:.|.:.::
Mouse   103 TGVNLESSFVKDQGLYVTVFGNPEAVTNAENEIFKWCQKQYLPLTLISKQEHCFFLNQTGNKSQD 167

  Fly   194 IERVTATRINIPSQSDESEFITIAGTKEGIAQAEQEIRQLSAEQYKKSSDRITVPKVYHPFIVGP 258
            :|:.......|.|..:::..|......:...::.......||...|.....:.:.|.::|..|.|
Mouse   168 LEQEGQINTQITSPHNQNNSINSVDVNQTKMKSSDGSLSTSARSNKGDIQILEMEKSFNPLTVKP 232

  Fly   259 YSENLNKLQE-------------ETGARINVPPQQVQKDEIVISGEKDAVAAAKAKVEAIYKDME 310
            |.:..:..||             ||...||  ..|:..|:|                ..:..||.
Mouse   233 YLQASDIFQETEEHVPFELSSAKETDLDIN--EGQLHVDQI----------------GCLKNDMI 279

  Fly   311 KKCSTVSVEV----------AKPKHRYVIGPKGSTIAEILQLTGVSVEMPPNDSPSETITLRGPQ 365
            ||.||::..:          :..:|         .:.|||..:..|.....::|.|:.:|.....
Mouse   280 KKTSTITEGMMMTFQDSGTRSLKRH---------FLEEILDTSEDSTGQSQSESISDYMTQHSDL 335

  Fly   366 VALGNALTVVYQKSNSVKSVEINAAHWIHKYVIGRKGANMKQLEEDCPNVNVN-CLEDKIKLEGD 429
            .:.|..........:...:..|.|..|:|:::||.||..:.::.|..|.|.:: ..:|||.|:|.
Mouse   336 DSSGELFNEADDNDDDYIASSIFAPSWLHRFIIGTKGEEISEITECVPKVQIHFTAKDKITLKGP 400

  Fly   430 PENVDRAVAYLSEIIKNYEENFTFEVMTVNPSYYKHIIGKAGANVNRLKDELKVNINI-EEREGQ 493
            .::|:.|......|:|:......:..:..:..:||::.|..|..:||:.::.:|:|.: .|.|..
Mouse   401 IDDVNYAQEKFDIIVKDLMSKMEYTEINSDSKFYKYLTGNNGEILNRITEKNQVSITMFPENESN 465

  Fly   494 NNIRIEGPKEGVRQAQLELQEKIDKLENEKSKDVIIDRRLHRSIIGAKGEKIREVKDRYRQVTIT 558
            .:|||||...||.||:.||.:..:.||.|.|:|:||..:.|..:||.|||::||:..::..|.:.
Mouse   466 YSIRIEGESLGVHQAKKELLDLANNLEEEYSQDIIIKHQFHHILIGQKGERVREICKKFPDVILN 530

  Fly   559 IPTPQENTDIVKLRGPKEDVDKCHKDLLKLVKEIQESSHIIEVPIFKQFHKFVIGKGGANIKKIR 623
            .|.|.|.:|||:|.||:.:.:||.:.|..::.:|:|:::.|.|||.|:.||.:||||.:||:||.
Mouse   531 FPHPAEKSDIVQLIGPRYESEKCAQYLENMLTDIKENNYSISVPIIKKLHKRIIGKGVSNIRKIS 595

  Fly   624 DETQTKIDLPAEGDTNEVIVITGKKENVLEAKERIQKIQNELSDIVTEEVQIPPKYYNSIIGTGG 688
            :.|.|||..|.|...:|..:|||..||...|:..|..:|.||:|...||:.||...|..:.....
Mouse   596 EATNTKITFPPESCNSEEFIITGYPENCEIARNWILSLQQELADTAEEEIIIPANLYKHLTNPKE 660

  Fly   689 KLISSIMEECGGVSIKFPNSDSKSDKVTIRGPKDDVEKAKVQLLELANERQLASFTAEVRAKQQH 753
            .|::||:||||.:.:.||...|..:|:.|.|..::|||||.:||:|:.|.|..:::..:..|.::
Mouse   661 CLLNSIIEECGKIHLHFPKGKSNLNKIIIMGTIENVEKAKTKLLKLSEEEQAKNYSETLHIKSKY 725

  Fly   754 HKFLIGKNGASIRKIRDATGARIIFPSNEDTDKEVITIIGKEESVKKAREQLEAIIKECDEVTEG 818
            |:||:.|||.:|.||.|.||..:.||:..:.|:|.|||.|.|||||:.::||:.::|:.:...:.
Mouse   726 HQFLLNKNGGNISKICDETGTCVFFPNPTNKDQETITITGTEESVKEVQKQLDDLVKDFENEVDD 790

  Fly   819 EVSVDPKHHKHFVAKRGFILHRISEECGGVMISFPRVGINSDKVTIKGAKDCIEAARQRIEEIVA 883
            .:.::.:.|.:||.:||.:|..::|:.|||:|:|...|..:.||||:|||.|:|||::.|:||..
Mouse   791 SILINRRFHHYFVMRRGQLLKEMAEDYGGVVITFSYSGRQNTKVTIRGAKPCVEAAKKHIKEIFE 855

  Fly   884 DLEAQTTIEVVIPQRHHRTIMGARGFKVQQVTFEFDVQIKFPDRDATEPVEGLTNGGSGENGGEN 948
            .|.:|.|...|:|......|||....::||:..::.|:|||||.:  :|...:      :.|...
Mouse   856 PLGSQITTRYVLPHSFQPFIMGPISSRIQQIARDYKVEIKFPDIE--KPALNM------DLGTHE 912

  Fly   949 EGQEGEQEVEKEAEQEPVRQCDVIRITGRIEKCEAAKQALLDLIPIEEELSVPFDLHRTIIGPRG 1013
            :|:|..:...||......|:.|.|.|:|::|.|:||.:||..:||:..|:.||..|...|||.:|
Mouse   913 KGKEKWKRTAKEIAPNSPRKGDTIFISGQVENCKAATEALASIIPVTTEVHVPLHLQPYIIGHKG 977

  Fly  1014 ANVRQFMSKHDVHVELPPSELKSDVIKVCGTPARVAEAREALVKMIEDYEADRADRELRSFVLQV 1078
            :.:|:.:.:::||:::......||:|.:.|..|.|.:|:..|.|.::..:.:..||.||:|.|..
Mouse   978 SGLRKLVKEYEVHMQVSQPGKNSDIISIMGLSANVEQAKIKLQKRVKSLQMEVEDRTLRNFKLMF 1042

  Fly  1079 DVDTEFHSKLIGRHGAVINKLRADHDVIISLPKRDEPN-DRIISITGYQANAEAARDAILEIVGD 1142
            ::|.::.:|:.|..|.:|.::..:|||.|..||:...: ...|:||||:.|..||||||:.::..
Mouse  1043 NLDPKYQAKITGHKGLLITQICTEHDVTIHFPKKGTHDMQEQITITGYKENTLAARDAIMRLLHK 1107

  Fly  1143 PETLHREVIEIDKRIHPHLIGQRRRTIRKIIEDNKVNIKFSADD-DNPNSIFISGKIEDVENVKE 1206
            .|....:.|.:::::..::||.|.:||.||::..:|:|:..... .||| |.::|..::||...|
Mouse  1108 IEKTISKEITLNQQVRGNVIGVRGKTINKIMDQYQVDIRLPPKGLYNPN-ITVTGLADNVEKAIE 1171

  Fly  1207 LLFGMAEDYERDYLD------------------NVAIAPPTIGAFLTGQGSGSDAAGASENGFVI 1253
            .:..:    |:.||.                  |:|:.|                    ...||.
Mouse  1172 HILNL----EKYYLSAAINHGSQQEQPKSMSLCNIAMTP--------------------SKSFVR 1212

  Fly  1254 KDAPWEKQKQAKNLT-APNTQSQEDFP 1279
            |..|.    .||..| .|:..:.|.||
Mouse  1213 KYVPC----YAKTTTKLPDVDNCEHFP 1235

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dp1	NP_523781.2	KH-I_Vigilin_rpt1	95..162	CDD:411833	19/66 (29%)
		KH-I_Vigilin_rpt2	165..239	CDD:411834	9/73 (12%)
		KH-I_Vigilin_rpt3	243..>290	CDD:411835	14/59 (24%)
		KH-I_Vigilin_rpt4	315..376	CDD:411836	10/70 (14%)
		KH-I_Vigilin_rpt5	382..449	CDD:411837	20/67 (30%)
		KH-I_Vigilin_rpt6	451..517	CDD:411804	21/66 (32%)
		KH-I_Vigilin_rpt7	522..588	CDD:411838	26/65 (40%)
		KH-I_Vigilin_rpt8	599..659	CDD:411839	28/59 (47%)
		KH-I_Vigilin_rpt9	668..737	CDD:411840	26/68 (38%)
		KH-I_Vigilin_rpt10	741..806	CDD:411841	27/64 (42%)
		KH-I_Vigilin_rpt11	817..882	CDD:411842	26/64 (41%)
		KH-I_Vigilin_rpt12	890..991	CDD:411843	31/100 (31%)
		KH-I_Vigilin_rpt13	993..1070	CDD:411844	22/76 (29%)
		KH-I_Vigilin_rpt14	1074..1144	CDD:411845	25/70 (36%)
		KH-I_Vigilin_rpt15	1147..1214	CDD:411846	18/67 (27%)
Gm382	NP_001028413.2	KH-I	71..136	CDD:469614	19/66 (29%)
		KH-I	352..420	CDD:469614	20/67 (30%)
		KH-I	422..489	CDD:469614	21/66 (32%)
		KH-I	494..560	CDD:469614	26/65 (40%)
		KH-I_Vigilin_rpt8	570..631	CDD:411839	28/60 (47%)
		KH-I	641..709	CDD:469614	26/67 (39%)
		KH-I	713..777	CDD:469614	26/63 (41%)
		KH-I	789..853	CDD:469614	25/63 (40%)
		KH-I	866..952	CDD:469614	28/93 (30%)
		KH-I	957..1033	CDD:469614	21/75 (28%)
		KH-I	1038..1110	CDD:469614	25/71 (35%)
		KH-I	1112..1177	CDD:469614	18/69 (26%)