Protein Alignment Dp1 and vgln-1

DIOPT Version :10

• Sequence 1: NP_523781.2
• Gene: Dp1 / 37116
• FlyBaseID: FBgn0027835
• Length: 1301
• Species: Drosophila melanogaster
• Sequence 2: NP_496136.1
• Gene: vgln-1 / 174543
• WormBaseID: WBGene00007463
• Length: 1220
• Species: Caenorhabditis elegans
• Alignment Length: 1303
• Identity: 456/1303 - (34%)
• Similarity: 726/1303 - (55%)
• Gaps: 104/1303 - (7%)

  Fly     7 MEETNNATTIEQQPIALINGQEQVANEQQPSSPTSVATPTSTTSGGTGNATPAFSYDDLFPALPA 71
            :|||||   :|..|                               .||.|..:|||...||.||.
 Worm     6 IEETNN---VEIDP-------------------------------ATGGAVMSFSYASDFPTLPD 36

  Fly    72 NTSAQSQSGASGSTLARVT-SSQKTHIVHVPCKERKSTESEKFGE-GESKRICQQITKETGAQIE 134
            ...|.:.:.......:|.| |..:.:|......:.:|.:.:.||. .|..:..|.|...|..:||
 Worm    37 AAPASAPTAKQTHVWSRPTLSKSEVNITFRLASDERSNKVKSFGSTSEESKKAQAIATATKTRIE 101

  Fly   135 IVSGKNQSLTFLIKGKQSELLDARRKILMGFSTQASRQVTVPREHFRVILGKGGQRLREIERVTA 199
            :...|:..||.::||::::..:||.:|:....|||||::.:|::|...::||.|..||.:|..|.
 Worm   102 LSESKDGELTVVVKGERAKAEEARARIIRDLQTQASREIDIPKDHHGRLIGKEGALLRNLEAETN 166

  Fly   200 TRINIPSQSDESEFITIAGTKEGIAQAEQEIRQLSAEQYKKSSDRITVPKVYHPFIVGPYSENLN 264
            .||.||::...|..|||.|.:|||.:|...|..:|..:.|.:::.|..||....|:.||.:|..:
 Worm   167 CRIQIPNRDGPSSKITITGPREGIQRAAAHILAVSEREAKLATEHIVCPKNLVAFVRGPKNETYD 231

  Fly   265 KLQEETGARINVPPQQVQKDEIVISGEKDAVAAAKAKVEAIYKDMEKKCSTVSVEVAKPKHRYVI 329
            :|.:..|.:||:||..|..:.|.::||||.|....|::..|. :.:|..|::.|.||:.:|||::
 Worm   232 RLTQNNGVKINIPPPHVTNEVISVTGEKDGVLRVAAEIRQII-ESKKNVSSIQVAVARTQHRYIV 295

  Fly   330 GPKGSTIAEILQLTGVSVEMPPNDSPSETITLRGPQVALGNALTVVYQKSNSVKSVEINAAHWIH 394
            |...|.|.::||.||..||:|..||.|:.:||.|....|..||.:|.::::||.:..|:|.:|:|
 Worm   296 GQSRSGIHDVLQKTGCVVEVPAEDSGSDQVTLIGNAQDLAKALALVIERASSVVTQSISAPNWLH 360

  Fly   395 KYVIGRKGANMKQLEEDCPNVNVNC-LEDKIKLEGDPENVDRAVAYLSEIIKNYEENFTFEVMTV 458
            |::||.|||.:..|..:..||.:.. ..::|.|||.||.|..|...||:.:...:.....|.:.|
 Worm   361 KHLIGPKGATLTALVPNRNNVQIEFDNSNQIFLEGSPEEVKLAFEPLSKEVARLQMELAIEKVKV 425

  Fly   459 NPSYYKHIIGKAGANVNRLKDELKVNINI-EEREGQNNIRIEGPKEGVRQAQLELQEKIDKLENE 522
            :|:.::|:||:.|:.::::||:..|.|.| .|....:.|.:||.||||::|..|::..:.|:|||
 Worm   426 HPTLHRHVIGRGGSLISKIKDQHGVQITIPNEETNSDEIVVEGKKEGVKKAVTEIRAIVTKIENE 490

  Fly   523 KSKDVIIDRRLHRSIIGAKGEKIREVKDRYRQVTITIPTPQENTDIVKLRGPKEDVDKCHKDLLK 587
            ||:|:||.:|||:.|||:||..::.::|.:..|::..|..:..:|:|.:||.|.:||..:|.|..
 Worm   491 KSRDIIIPQRLHKLIIGSKGSGVQVIRDSHPNVSVVFPDAKSKSDVVNIRGDKTEVDAVYKKLTA 555

  Fly   588 LVKEIQESSHIIEVPIFKQFHKFVIGKGGANIKKIRDETQTKIDLPAEGDTNEVIVITGKKENVL 652
            |.||..|:::...|.|||:|.|.::|||||:|:|:||||:|:||||..|..:..|.:|||:.||.
 Worm   556 LSKEYAENNYQQTVAIFKEFLKHIVGKGGASIRKLRDETETRIDLPESGSDDGKITVTGKQANVE 620

  Fly   653 EAKERIQKIQNELSDIVTEEVQIPPKYYNSIIGTGGKLISSIMEECGGVSIKFPNSDSKSDKVTI 717
            :|..::.|||.||:::..|.::||.|..:...|.|.:|||.|.:|||||.|:||:..|:|.||||
 Worm   621 KAVAQLNKIQEELANVAEESIEIPQKVQSRFFGNGRRLISDIEDECGGVHIRFPSEKSESTKVTI 685

  Fly   718 RGPKDDVEKAKVQLLELANERQLASFTAEVRAKQQHHKFLIGKNGASIRKIRDATGARIIFPSNE 782
            |||..||.||...|..||.:::.......|:||.:.|:|||||.|:.|.|:||....|::||...
 Worm   686 RGPAGDVAKAVGLLSALAKDKEENYVEDTVKAKPEFHRFLIGKGGSKIAKLRDTLNVRVMFPKEG 750

  Fly   783 DTDKEVITIIGKEESVKKAREQLEAIIKECDEVTEGEVSVDPKHHKHFVAKRGFILHRISEECGG 847
            |.:||.|.::||:|.|.||:..||..||:..|..:.:::||||::|:|:|:...::..|.|:.||
 Worm   751 DAEKETIHLLGKKEDVPKAKAALEDAIKQLSETVDIKITVDPKYYKNFLARGAALVKEIQEQNGG 815

  Fly   848 VMISFPRVGINSDKVTIKGAKDCIEAARQRIEEIVADLEAQTTIEVVIPQRHHRTIMGARGFKVQ 912
            |:||||:.|.:|.:|:|:|:|.|:|||:.|||::|.|.|.|.|..|.||.:.||.::..||.|:.
 Worm   816 VVISFPKNGTDSSEVSIRGSKQCVEAAKNRIEDVVEDYEKQITDNVTIPAQFHRGLLAGRGAKIH 880

  Fly   913 QVTFEFDVQIKFPDRDATEPVEGLTNGGSGENGGENEGQEGEQEVEKEAEQEPVRQCDVIRITGR 977
            ::..:::|.|:||:                   ...||.||.               |.:.::||
 Worm   881 ELQSKYNVSIRFPN-------------------NREEGSEGS---------------DQVTVSGR 911

  Fly   978 IEKCEAAKQALLDLIPIEEELSVPFDLHRTIIGPRGANVRQFMSKHDVHVELPPSELKSDVIKVC 1042
            ..|.|.||:|||.::||.:.:.:|.|:||:|||..|..||:.|..:||::.:|......| |.|.
 Worm   912 DTKVEEAKEALLAMVPISKVIQLPVDMHRSIIGRGGETVRKLMQDYDVNISIPKDNSSED-ITVT 975

  Fly  1043 GTPARVAEAREALVKMIEDYEADRADRELRSFVLQVDVDTEFHSKLIGRHGAVINKLRADHDVII 1107
            |....|.:|.|||...:.:|||...||:|:.:.:.::|.|::|.|:||:.||.|..|:..:.|||
 Worm   976 GQTENVDQALEALRGKLGEYEAQAEDRKLKQWSMSINVPTDYHQKIIGQRGATITALKEKYGVII 1040

  Fly  1108 SLPKRDEPNDRIISITGYQANAEAARDAILEIVGDPETLHREVIEIDKRIHPHLIGQRRRTIRKI 1172
            ::|:.|  .:..|:|.||:..|.....||.|::.:..::..:.|.:|.|.||.|||||.:.::|:
 Worm  1041 NVPRED--GNETITIQGYEEKANECAAAIEEMISELRSMFTQEISLDARYHPRLIGQRGKNLKKV 1103

  Fly  1173 IEDNKVNIKF---SADDDNPNSIFISGKIEDVENVKELLFGMAEDYERDYLDNVA----IAPPTI 1230
            :||.:|.|:.   .|:|  ||.:.::||  |..:|.:.:..:..:.|...||||.    ::|
 Worm  1104 MEDYRVEIRLPRQGAED--PNLVVVAGK--DENDVYDCIDHLRAEEEEFLLDNVERTQYMSP--- 1161

  Fly  1231 GAFLTGQGSGSDAAGASENGFVIKDAPWEKQKQAKNLTAPNTQSQEDFPHFAAGGAPVASTPITS 1295
                ..|.|.:...........:|.|||:.          :..|.|.||.........|:.....
 Worm  1162 ----RQQESNNTRHHQQPTSVQMKGAPWQL----------DLGSSEQFPDMGPAAGSSAAVGGAG 1212

  Fly  1296 VWG 1298
            .||
 Worm  1213 AWG 1215

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dp1	NP_523781.2	KH-I_Vigilin_rpt1	95..162	CDD:411833	17/67 (25%)
		KH-I_Vigilin_rpt2	165..239	CDD:411834	29/73 (40%)
		KH-I_Vigilin_rpt3	243..>290	CDD:411835	15/46 (33%)
		KH-I_Vigilin_rpt4	315..376	CDD:411836	25/60 (42%)
		KH-I_Vigilin_rpt5	382..449	CDD:411837	24/67 (36%)
		KH-I_Vigilin_rpt6	451..517	CDD:411804	22/66 (33%)
		KH-I_Vigilin_rpt7	522..588	CDD:411838	26/65 (40%)
		KH-I_Vigilin_rpt8	599..659	CDD:411839	30/59 (51%)
		KH-I_Vigilin_rpt9	668..737	CDD:411840	34/68 (50%)
		KH-I_Vigilin_rpt10	741..806	CDD:411841	27/64 (42%)
		KH-I_Vigilin_rpt11	817..882	CDD:411842	29/64 (45%)
		KH-I_Vigilin_rpt12	890..991	CDD:411843	27/100 (27%)
		KH-I_Vigilin_rpt13	993..1070	CDD:411844	29/76 (38%)
		KH-I_Vigilin_rpt14	1074..1144	CDD:411845	23/69 (33%)
		KH-I_Vigilin_rpt15	1147..1214	CDD:411846	23/69 (33%)
vgln-1	NP_496136.1	KH-I	65..129	CDD:469614	16/63 (25%)
		KH-I_ScSCP160_rpt6	136..204	CDD:411879	27/67 (40%)
		KH-I_Vigilin_rpt3	209..270	CDD:411835	21/60 (35%)
		KH-I_Vigilin_rpt4	281..341	CDD:411836	25/59 (42%)
		KH-I_Vigilin_rpt5	348..416	CDD:411837	24/67 (36%)
		KH-I_Vigilin_rpt6	418..485	CDD:411804	22/66 (33%)
		KH-I_Vigilin_rpt7	490..556	CDD:411838	26/65 (40%)
		KH-I_Vigilin_rpt8	566..627	CDD:411839	30/60 (50%)
		KH-I	636..705	CDD:469614	34/68 (50%)
		KH-I_Vigilin_rpt10	709..774	CDD:411841	27/64 (42%)
		KH-I_Vigilin_rpt11	785..850	CDD:411842	29/64 (45%)
		KH-I	861..926	CDD:469614	26/98 (27%)
		KH-I	927..1003	CDD:469614	29/76 (38%)
		KH-I_Vigilin_rpt14	1007..1076	CDD:411845	23/70 (33%)
		KH-I_Vigilin_rpt15	1078..1147	CDD:411846	23/72 (32%)