Protein Alignment GstE8 and CLIC3

DIOPT Version :10

• Sequence 1: NP_611330.2
• Gene: GstE8 / 37113
• FlyBaseID: FBgn0063492
• Length: 222
• Species: Drosophila melanogaster
• Sequence 2: NP_004660.2
• Gene: CLIC3 / 9022
• HGNCID: 2064
• Length: 236
• Species: Homo sapiens
• Alignment Length: 228
• Identity: 48/228 - (21%)
• Similarity: 88/228 - (38%)
• Gaps: 53/228 - (23%)

  Fly    13 PPVRAAKLTLAALGIPYEYVKINTLAKETLSPEFLRK-NPQHTVPTLEDDGHFIWDSHAISAYLV 76
            |..:...:.|...|:|:....::|    ..||:.|:. .|...:|.|      ::||.|.:..|.
Human    23 PSCQRLFMVLLLKGVPFTLTTVDT----RRSPDVLKDFAPGSQLPIL------LYDSDAKTDTLQ 77

  Fly    77 SKYGQSDTLYPKDLLQRAVVDQRLHFESGVVFVNGLRGITKPLFATGQTTIPKERYDAVIEIYDF 141
            .:....:||.|.|....|...:..:.....||......|..|:.|..:..     |..::.....
Human    78 IEDFLEETLGPPDFPSLAPRYRESNTAGNDVFHKFSAFIKNPVPAQDEAL-----YQQLLRALAR 137

  Fly   142 VETFLTG---HD-------------FIAGDQLTIADFSLITSITALAVFVVIDTV----KYANIT 186
            ::::|..   |:             |:.||:||:||.||:..:.      ::|||    :.|.|.
Human   138 LDSYLRAPLEHELAGEPQLRESRRRFLDGDRLTLADCSLLPKLH------IVDTVCAHFRQAPIP 196

  Fly   187 AWIKRIEELPYYEEACGKGARDLVTLLKKFNFT 219
            |.::.:..  |.:.|..:         |:|.:|
Human   197 AELRGVRR--YLDSAMQE---------KEFKYT 218

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GstE8	NP_611330.2	GstA	4..209	CDD:440390	45/216 (21%)
CLIC3	NP_004660.2	Required for insertion into the membrane. /evidence=ECO:0000250	1..88		17/74 (23%)
		O-ClC	5..229	CDD:129941	48/228 (21%)
		G-site. /evidence=ECO:0000305|PubMed:28198360, ECO:0000305|PubMed:37759794	22..25		1/1 (100%)