DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment GstE8 and TEF4

DIOPT Version :9

Sequence 1:	NP_001286571.1	Gene:	GstE8 / 37113	FlyBaseID:	FBgn0063492	Length:	222	Species:	Drosophila melanogaster
Sequence 2:	NP_012842.1	Gene:	TEF4 / 853781	SGDID:	S000001564	Length:	412	Species:	Saccharomyces cerevisiae

Alignment Length:	209	Identity:	43/209 - (20%)
Similarity:	84/209 - (40%)	Gaps:	26/209 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSKLILYGTEASPPVRAAKLTLAALGIPYEYVKINTLAKETLSPEFLRKNPQHTVPT-LEDDGHF 64
            ||:..|| ...||...|::..::...:.   |||..|.:   |.||....|....|. |...|..
Yeast     1 MSQGTLY-INRSPRNYASEALISYFKLD---VKIVDLEQ---SSEFASLFPLKQAPAFLGPKGLK 58

  Fly    65 IWDSHAISAYLVSKYG---QSDTLYPKDLLQRAVVDQRLHFESGVVFVNGLRGITKPLFATGQTT 126
            :.::.||..||.::..   :...|...|:::::.:.:.....:..|..|    |.:| |.:.:..
Yeast    59 LTEALAIQFYLANQVADEKERARLLGSDVIEKSQILRWASLANSDVMSN----IARP-FLSFKGL 118

  Fly   127 IPKERYD---AVIEIYDFVETF---LTGHDFIAGDQLTIADFSLITSITALAVFVVID---TVKY 182
            ||..:.|   ..::|.:....|   |..:.|:|.:.:::.|.....| .|..:..::.   ..|:
Yeast   119 IPYNKKDVDACFVKIDNLAAVFDARLRDYTFVATENISLGDLHAAGS-WAFGLATILGPEWRAKH 182

  Fly   183 ANITAWIKRIEELP 196
            .::..|...:...|
Yeast   183 PHLMRWFNTVAASP 196

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE8	NP_001286571.1	GstA	4..196	CDD:223698	40/204 (20%)
		GST_N_Delta_Epsilon	4..77	CDD:239343	20/73 (27%)
		GST_C_Delta_Epsilon	91..209	CDD:198287	19/115 (17%)
TEF4	NP_012842.1	GST_N_EF1Bgamma	4..72	CDD:239342	20/74 (27%)
		GST_C_EF1Bgamma_like	89..211	CDD:198290	19/114 (17%)
		EF1G	253..356	CDD:395522
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157345103
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740