DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstE8 and GTT2

DIOPT Version :9

Sequence 1:	NP_001286571.1	Gene:	GstE8 / 37113	FlyBaseID:	FBgn0063492	Length:	222	Species:	Drosophila melanogaster
Sequence 2:	NP_013040.1	Gene:	GTT2 / 850666	SGDID:	S000003983	Length:	233	Species:	Saccharomyces cerevisiae

Alignment Length:	204	Identity:	56/204 - (27%)
Similarity:	95/204 - (46%)	Gaps:	11/204 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 KLILYGTEASPPVRAAKLTLAALGI--PYEYVKINTLAKETLSPEFLRKNPQHTVPTLE-DDGHF 64
            |:|:|.|.|.|.....::.||...:  ..::|:||....|...||||.||...|||.|| |||..
Yeast    18 KMIIYDTPAGPYPARVRIALAEKNMLSSVQFVRINLWKGEHKKPEFLAKNYSGTVPVLELDDGTL 82

  Fly    65 IWDSHAISAYLVSKYGQSDTLYPKDLLQRAVV---DQRLHFE----SGVVFVNGLRGITKPLFAT 122
            |.:..||:.|:.:..| :.||..|..|::.|:   ::|...|    ..|.|.:...|:...:...
Yeast    83 IAECTAITEYIDALDG-TPTLTGKTPLEKGVIHMMNKRAELELLDPVSVYFHHATPGLGPEVELY 146

  Fly   123 GQTTIPKERYDAVIEIYDFVETFLTGHDFIAGDQLTIADFSLITSITALAVFVVIDTVKYANITA 187
            ........:.|..:....:.:|.|....::|||..::||.::|..:...|:..:....:...:.|
Yeast   147 QNKEWGLRQRDKALHGMHYFDTVLRERPYVAGDSFSMADITVIAGLIFAAIVKLQVPEECEALRA 211

  Fly   188 WIKRIEELP 196
            |.||:::.|
Yeast   212 WYKRMQQRP 220

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE8	NP_001286571.1	GstA	4..196	CDD:223698	54/201 (27%)
		GST_N_Delta_Epsilon	4..77	CDD:239343	29/75 (39%)
		GST_C_Delta_Epsilon	91..209	CDD:198287	22/113 (19%)
GTT2	NP_013040.1	GST_N_GTT2_like	19..94	CDD:239349	29/74 (39%)
GTT2	NP_013040.1	GST_C_GTT2_like	106..222	CDD:198291	22/115 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157345142
Domainoid	1	1.000	43	1.000	Domainoid score	I3172
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	68	1.000	Inparanoid score	I1708
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000035
OrthoInspector	1	1.000	-	-		oto99351
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.790