Protein Alignment GstE8 and GSTT2B

DIOPT Version :10

• Sequence 1: NP_611330.2
• Gene: GstE8 / 37113
• FlyBaseID: FBgn0063492
• Length: 222
• Species: Drosophila melanogaster
• Sequence 2: NP_001074312.1
• Gene: GSTT2B / 653689
• HGNCID: 33437
• Length: 244
• Species: Homo sapiens
• Alignment Length: 221
• Identity: 61/221 - (27%)
• Similarity: 98/221 - (44%)
• Gaps: 29/221 - (13%)

  Fly    12 SPPVRAAKLTLAALGIPYEYVKINTLAKETLSPEFLRKNPQHTVPTLEDDGHFIWDSHAISAYLV 76
            |.|.||..:.....|||.|...::.:..:..|.|||:.|....:|||:|....:.:|.||..||.
Human    11 SQPSRAVYIFAKKNGIPLELRTVDLVKGQHKSKEFLQINSLGKLPTLKDGDFILTESSAILIYLS 75

  Fly    77 SKYGQSDTLYPKDLLQRAVVDQRLHFESGVVFVNGLRGI------TKPLFATGQTTIPKERYD-- 133
            .||...|..||.||..||.|.:.|.:.:..  :.|..||      ..||..   ..:|:|:.:
Human    76 CKYQTPDHWYPSDLQARARVHEYLGWHADC--IRGTFGIPLWVQVLGPLIG---VQVPEEKVERN 135

  Fly   134 --AVIEIYDFVE-TFLTGHDFIAGDQLTIADFSLITSITALAVFVVIDTVKY------ANITAWI 189
              |:.:...::| .||....|:||.|:|:||      :.||...:....:.|      ..:.||.
Human   136 RTAMDQALQWLEDKFLGDRPFLAGQQVTLAD------LMALEELMQPVALGYELFEGRPRLAAWR 194

  Fly   190 KRIEELPYYEEACGKGARDLVTLLKK 215
            .|:|.. ...|.|.:....::::|::
Human   195 GRVEAF-LGAELCQEAHSIILSILEQ 219

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GstE8	NP_611330.2	GstA	4..209	CDD:440390	60/213 (28%)
GSTT2B	NP_001074312.1	GST_N_Theta	3..78	CDD:239348	22/66 (33%)
		GST_C_Theta	91..216	CDD:198292	31/136 (23%)