DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstE8 and CLIC5

DIOPT Version :9

Sequence 1:	NP_001286571.1	Gene:	GstE8 / 37113	FlyBaseID:	FBgn0063492	Length:	222	Species:	Drosophila melanogaster
Sequence 2:	NP_001107558.1	Gene:	CLIC5 / 53405	HGNCID:	13517	Length:	410	Species:	Homo sapiens

Alignment Length:	173	Identity:	40/173 - (23%)
Similarity:	62/173 - (35%)	Gaps:	76/173 - (43%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 KINTLAKETLSPEFLRKNPQHTVPTLEDDGHFIWDSHAISAYLVSKYGQSDT----------LYP 87
            ||....:|||:||   |.|:                      |.:|:.:|:|          .|.
Human   246 KIEEFLEETLTPE---KYPK----------------------LAAKHRESNTAGIDIFSKFSAYI 285

  Fly    88 KDLLQR--AVVDQRLHFESGVVFVNGLRGITKPLFATG---QTTIPKERYDAVIEIYDFVETFLT 147
            |:..|:  |.::               ||:||.|....   .|.:|:|           ::....
Human   286 KNTKQQNNAALE---------------RGLTKALKKLDDYLNTPLPEE-----------IDANTC 324

  Fly   148 GHD------FIAGDQLTIADFSLITSITALAVFVVIDTVKYAN 184
            |.|      |:.||:||:||.:|:..:..    |.|...||.|
Human   325 GEDKGSRRKFLDGDELTLADCNLLPKLHV----VKIVAKKYRN 363

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE8	NP_001286571.1	GstA	4..196	CDD:223698	40/173 (23%)
		GST_N_Delta_Epsilon	4..77	CDD:239343	10/43 (23%)
		GST_C_Delta_Epsilon	91..209	CDD:198287	25/105 (24%)
CLIC5	NP_001107558.1	O-ClC	173..408	CDD:129941	40/173 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165154554
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930