DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstE8 and GstE4

DIOPT Version :9

Sequence 1:	NP_001286571.1	Gene:	GstE8 / 37113	FlyBaseID:	FBgn0063492	Length:	222	Species:	Drosophila melanogaster
Sequence 2:	NP_611326.1	Gene:	GstE4 / 37109	FlyBaseID:	FBgn0063496	Length:	222	Species:	Drosophila melanogaster

Alignment Length:	219	Identity:	129/219 - (58%)
Similarity:	166/219 - (75%)	Gaps:	0/219 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSKLILYGTEASPPVRAAKLTLAALGIPYEYVKINTLAKETLSPEFLRKNPQHTVPTLEDDGHFI 65
            |.|:.|||.:||||.||..|||.||.:|:|:|.:|...||..|.:|.:||||||||.|:||...|
  Fly     1 MGKISLYGLDASPPTRACLLTLKALDLPFEFVFVNLFEKENFSEDFSKKNPQHTVPLLQDDDACI 65

  Fly    66 WDSHAISAYLVSKYGQSDTLYPKDLLQRAVVDQRLHFESGVVFVNGLRGITKPLFATGQTTIPKE 130
            ||||||.||||.||..||.||||||||||.|||.:||||||:|.:.||.:|:|:...|:.|:|:.
  Fly    66 WDSHAIMAYLVEKYAPSDELYPKDLLQRAKVDQLMHFESGVIFESALRRLTRPVLFFGEPTLPRN 130

  Fly   131 RYDAVIEIYDFVETFLTGHDFIAGDQLTIADFSLITSITALAVFVVIDTVKYANITAWIKRIEEL 195
            :.|.::::||||||||..|||:|||||||||||::::||::.||:.:|..||..|.||::|::||
  Fly   131 QVDHILQVYDFVETFLDDHDFVAGDQLTIADFSIVSTITSIGVFLELDPAKYPKIAAWLERLKEL 195

  Fly   196 PYYEEACGKGARDLVTLLKKFNFT 219
            ||||||.||||...|.||:..|||
  Fly   196 PYYEEANGKGAAQFVELLRSKNFT 219

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE8	NP_001286571.1	GstA	4..196	CDD:223698	110/191 (58%)
		GST_N_Delta_Epsilon	4..77	CDD:239343	43/72 (60%)
		GST_C_Delta_Epsilon	91..209	CDD:198287	67/117 (57%)
GstE4	NP_611326.1	GST_N_Delta_Epsilon	4..77	CDD:239343	43/72 (60%)
		GstA	6..196	CDD:223698	110/189 (58%)
		GST_C_Delta_Epsilon	91..209	CDD:198287	67/117 (57%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45467957
Domainoid	1	1.000	54	1.000	Domainoid score	I4138
eggNOG	1	0.900	-	-		E1_COG0625
Homologene	1	1.000	-	-		H120001
Inparanoid	1	1.050	77	1.000	Inparanoid score	I2398
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D118089at33392
OrthoFinder	1	1.000	-	-		FOG0000035
OrthoInspector	1	1.000	-	-		mtm975
orthoMCL	1	0.900	-	-		OOG6_100130
Panther	1	1.100	-	-	P	PTHR43969
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X30
	12	11.800