DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstE8 and mars1

DIOPT Version :9

Sequence 1:	NP_001286571.1	Gene:	GstE8 / 37113	FlyBaseID:	FBgn0063492	Length:	222	Species:	Drosophila melanogaster
Sequence 2:	NP_956370.1	Gene:	mars1 / 338183	ZFINID:	ZDB-GENE-030219-83	Length:	922	Species:	Danio rerio

Alignment Length:	194	Identity:	38/194 - (19%)
Similarity:	69/194 - (35%)	Gaps:	47/194 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 LRKNPQHTVPTLE---------DDGHFIWDSHAISAYLVSKYGQSDT-------LYPKDLLQRAV 95
            |.|:.:..||.|.         ..|..::..::|..||....||..|       .:....||.||
Zfish    30 LVKHEEKVVPYLTHPVLPILQLPSGQHLFSPNSICQYLFDVSGQKATDATNQWLEWEATNLQPAV 94

  Fly    96 VDQRLHFESGVVFVNGLR----GITKPLFATGQTTIPKERYDAVIEIYDFVETFLTGHDFIAGDQ 156
            : |.|.    :|.:.|.|    .:.|...:..:.::.|.:                 ..|:..:.
Zfish    95 L-QSLQ----LVALQGKRVEAAAVMKEPLSWLEQSLSKRK-----------------TSFLTDEV 137

  Fly   157 LTIADFSLITSITALAVFVVIDTVKYANITAWIKRIEELPYYEEAC-----GKGARDLVTLLKK 215
            :::||..|..::..|......:......:..|.:|:..:...:.|.     ||||..|.:.|:|
Zfish   138 VSVADVVLWAALYPLLSDSAFEPGDLQAVRGWFERVCSVSACQSAALRVLQGKGAEALKSFLQK 201

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE8	NP_001286571.1	GstA	4..196	CDD:223698	30/168 (18%)
		GST_N_Delta_Epsilon	4..77	CDD:239343	9/38 (24%)
		GST_C_Delta_Epsilon	91..209	CDD:198287	23/126 (18%)
mars1	NP_956370.1	GstA	1..173	CDD:223698	29/164 (18%)
		GST_N_family	1..67	CDD:238319	7/36 (19%)
		GST_C_MetRS_N	75..176	CDD:198340	19/122 (16%)
		PRK12268	261..820	CDD:237029
		MetRS_core	263..631	CDD:173907
		Anticodon_Ia_Met	640..769	CDD:153411
		MetRS_RNA	866..910	CDD:238475
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900