back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment GstE8 and GSTT2

DIOPT Version :9

Sequence 1:	NP_001286571.1	Gene:	GstE8 / 37113	FlyBaseID:	FBgn0063492	Length:	222	Species:	Drosophila melanogaster
Sequence 2:	NP_000845.2	Gene:	GSTT2 / 2953	HGNCID:	4642	Length:	244	Species:	Homo sapiens

Alignment Length:	221	Identity:	62/221 - (28%)
Similarity:	98/221 - (44%)	Gaps:	29/221 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 SPPVRAAKLTLAALGIPYEYVKINTLAKETLSPEFLRKNPQHTVPTLEDDGHFIWDSHAISAYLV 76
            |.|.||..:.....|||.|...::.:..:..|.|||:.|....:|||:|....:.:|.||..||.
Human    11 SQPSRAVYIFAKKNGIPLELRTVDLVKGQHKSKEFLQINSLGKLPTLKDGDFILTESSAILIYLS 75

  Fly    77 SKYGQSDTLYPKDLLQRAVVDQRLHFESGVVFVNGLRGI------TKPLFATGQTTIPKERYD-- 133
            .||...|..||.||..||.|.:.|.:.:..  :.|..||      ..||..   ..:|||:.:
Human    76 CKYQTPDHWYPSDLQARARVHEYLGWHADC--IRGTFGIPLWVQVLGPLIG---VQVPKEKVERN 135

  Fly   134 --AVIEIYDFVE-TFLTGHDFIAGDQLTIADFSLITSITALAVFVVIDTVKY------ANITAWI 189
              |:.:...::| .||....|:||.|:|:||      :.||...:....:.|      ..:.||.
Human   136 RTAMDQALQWLEDKFLGDRPFLAGQQVTLAD------LMALEELMQPVALGYELFEGRPRLAAWR 194

  Fly   190 KRIEELPYYEEACGKGARDLVTLLKK 215
            .|:|.. ...|.|.:....::::|::
Human   195 GRVEAF-LGAELCQEAHSIILSILEQ 219

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.