Protein Alignment GstE8 and GSTO2

DIOPT Version :10

• Sequence 1: NP_611330.2
• Gene: GstE8 / 37113
• FlyBaseID: FBgn0063492
• Length: 222
• Species: Drosophila melanogaster
• Sequence 2: NP_899062.1
• Gene: GSTO2 / 119391
• HGNCID: 23064
• Length: 243
• Species: Homo sapiens
• Alignment Length: 200
• Identity: 48/200 - (24%)
• Similarity: 81/200 - (40%)
• Gaps: 29/200 - (14%)

  Fly     6 LYGTEASPPVRAAKLTLAALGIPYEYVKINTLAKETLSPE-FLRKNPQHTVPTLE-DDGHFIWDS 68
            :|.....|.....:|.|.|..|.:|.|.||...|    || :..|:|...:|.|| .....|::|
Human    26 IYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNK----PEWYYTKHPFGHIPVLETSQCQLIYES 86

  Fly    69 HAISAYLVSKY-GQSDTLYPKDLLQRAVVDQRLHFESGVVFVNGLRGITKPLF--------ATGQ 124
            .....||...| |:.  |:|.|..:||  .|::..|   :|.. :..:||...        .|..
Human    87 VIACEYLDDAYPGRK--LFPYDPYERA--RQKMLLE---LFCK-VPHLTKECLVALRCGRECTNL 143

  Fly   125 TTIPKERYDAVIEIYDFVETFLTGHDFIAGDQLTIADFSLITSITALAVFVVIDTVKYA-NITAW 188
            ....::.:..:.||.::..|     .|..|..:::.|:.|......|.|:.::|.|.:. .:..|
Human   144 KAALRQEFSNLEEILEYQNT-----TFFGGTCISMIDYLLWPWFERLDVYGILDCVSHTPALRLW 203

  Fly   189 IKRIE 193
            |..::
Human   204 ISAMK 208

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GstE8	NP_611330.2	GstA	4..209	CDD:440390	48/199 (24%)
GSTO2	NP_899062.1	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold	7..94	CDD:469754	21/71 (30%)
		GST_C_Omega	108..230	CDD:198293	21/111 (19%)