DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstE7 and TEF4

DIOPT Version :9

Sequence 1:	NP_611329.1	Gene:	GstE7 / 37112	FlyBaseID:	FBgn0063493	Length:	223	Species:	Drosophila melanogaster
Sequence 2:	NP_012842.1	Gene:	TEF4 / 853781	SGDID:	S000001564	Length:	412	Species:	Saccharomyces cerevisiae

Alignment Length:	228	Identity:	49/228 - (21%)
Similarity:	90/228 - (39%)	Gaps:	43/228 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LYGLEASPPVRAVKLTLAALEVPYEFVEVNTRAKENFSEEFLKKNPQHTVPT-LEDDGHYIWDSH 69
            || :..||...|.:..::..::..:.|::..      |.||....|....|. |...|..:.::.
Yeast     6 LY-INRSPRNYASEALISYFKLDVKIVDLEQ------SSEFASLFPLKQAPAFLGPKGLKLTEAL 63

  Fly    70 AIIAYLVSKYG---KTDSLYPKDLLQRAVVDQRLHFESGVIFANA--LRSITKPLFAGKQTMIP- 128
            ||..||.::..   :...|...|:::::   |.|.:.|   .||:  :.:|.:| |...:.:||
Yeast    64 AIQFYLANQVADEKERARLLGSDVIEKS---QILRWAS---LANSDVMSNIARP-FLSFKGLIPY 121

  Fly   129 -KERYDAIIEVYDFL----EKFLAGNDYVAGNQLTIADFSI-------ISTVSSLEVFVKVDTTK 181
             |:..||.....|.|    :..|....:||...:::.|...       ::|:...|.     ..|
Yeast   122 NKKDVDACFVKIDNLAAVFDARLRDYTFVATENISLGDLHAAGSWAFGLATILGPEW-----RAK 181

  Fly   182 YPRIAAWFKR-----LQKLPYYEEANGNGARTF 209
            :|.:..||..     :.|.|:.|......|.|:
Yeast   182 HPHLMRWFNTVAASPIVKTPFAEVKLAEKALTY 214

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE7	NP_611329.1	GstA	4..196	CDD:223698	45/213 (21%)
		GST_N_Delta_Epsilon	4..77	CDD:239343	17/71 (24%)
		GST_C_Delta_Epsilon	91..209	CDD:198287	29/137 (21%)
TEF4	NP_012842.1	GST_N_EF1Bgamma	4..72	CDD:239342	17/72 (24%)
		GST_C_EF1Bgamma_like	89..211	CDD:198290	28/133 (21%)
		EF1G	253..356	CDD:395522
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157345109
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740