DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment GstE7 and GDAP1L1

DIOPT Version :9

Sequence 1:	NP_611329.1	Gene:	GstE7 / 37112	FlyBaseID:	FBgn0063493	Length:	223	Species:	Drosophila melanogaster
Sequence 2:	NP_001243666.1	Gene:	GDAP1L1 / 78997	HGNCID:	4213	Length:	386	Species:	Homo sapiens

Alignment Length:	290	Identity:	54/290 - (18%)
Similarity:	99/290 - (34%)	Gaps:	109/290 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LILYGLEASPPVRAVKLTLAALEVPYEFVEVNTRAKENFSEEFLKKNPQHTVPTLEDDGHYIWDS 68
            |:||....|...:.|:|.:|...:..|..:|:....|:....|::.|....||.:....:.|.|.
Human    47 LVLYHWTQSFSSQKVRLVIAEKGLVCEERDVSLPQSEHKEPWFMRLNLGEEVPVIIHRDNIISDY 111

  Fly    69 HAIIAYLVSKY-----GKTDSLYP-----------------------------KDLLQRAVVDQR 99
            ..||.|:...:     |:..|.:|                             ::||....:|..
Human   112 DQIIDYVERTFTGGGRGRCPSGFPAQPLAVPTEHVVALMPEVGSLQHARVLQYRELLDALPMDAY 176

  Fly   100 LHFESGVI----------------------FANALRSITK-----------PLFAGKQTMIPKER 131
            .|   |.|                      .|||...:.|           |..:.::.::.|
Human   177 TH---GCILHPELTTDSMIPKYATAEIRRHLANATTDLMKLDHEEEPQLSEPYLSKQKKLMAK-- 236

  Fly   132 YDAIIEVYD--FLEKFLA------------------GND------YVAGNQLTIADFSIISTVSS 170
               |:|..|  :|:|.|.                  .|:      ::.|...|:||..:.:|:..
Human   237 ---ILEHDDVSYLKKILGELAMVLDQIEAELEKRKLENEGQKCELWLCGCAFTLADVLLGATLHR 298

  Fly   171 LEVFVKVDTTKY------PRIAAWFKRLQK 194
            |: |:.: :.||      |.:.::|:|:|:
Human   299 LK-FLGL-SKKYWEDGSRPNLQSFFERVQR 326

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE7	NP_611329.1	GstA	4..196	CDD:223698	54/290 (19%)
		GST_N_Delta_Epsilon	4..77	CDD:239343	19/72 (26%)
		GST_C_Delta_Epsilon	91..209	CDD:198287	31/169 (18%)
GDAP1L1	NP_001243666.1	GstA	47..333	CDD:223698	54/290 (19%)
		GST_N_GDAP1	47..119	CDD:239350	19/71 (27%)
		GST_C_GDAP1L1	220..330	CDD:198335	22/114 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165154532
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840