Protein Alignment GstE7 and GSTT4

DIOPT Version :10

• Sequence 1: NP_611329.1
• Gene: GstE7 / 37112
• FlyBaseID: FBgn0063493
• Length: 223
• Species: Drosophila melanogaster
• Sequence 2: NP_001345593.1
• Gene: GSTT4 / 25774
• HGNCID: 26930
• Length: 241
• Species: Homo sapiens
• Alignment Length: 245
• Identity: 60/245 - (24%)
• Similarity: 104/245 - (42%)
• Gaps: 49/245 - (20%)

  Fly     4 LILYGLEASPPVRAVKLTLAALEVPYEFVEVNTRAKENFSEEFLKKNPQHTVPTLEDDGHYIWDS 68
            |.||....|.|.|||.:.....::.:.|..|:.....:.|:.::..||...:|:|:|....:.:|
Human     3 LELYMDLLSAPCRAVYIFSKKHDIQFNFQFVDLLKGHHHSKGYIDINPLRKLPSLKDGKFILSES 67

  Fly    69 HAIIAYLVSKYGKTDSLYPKDLLQRAVVDQRLHFESGVIFANALRSIT-----KPLFAGKQTMIP 128
            .||:.||..||.......|.|...||.||:.:.::. ..|...::.|.     .|...|::....
Human    68 AAILYYLCRKYSAPSHWCPPDPHARARVDEFVAWQH-TAFQLPMKKIVWLKLLIPKITGEEVSAE 131

  Fly   129 KERYDAIIEVYD----FLEKFLAGNDYVAGNQLTIADFSIISTVSSLE-------VFVKVDTTKY 182
            |..: |:.||.:    |.|.||....::.|||:::||  :::.|..::       ||:...
Human   132 KMEH-AVEEVKNSLQLFEEYFLQDKMFITGNQISLAD--LVAVVEMMQPMAANYNVFLNSS---- 189

  Fly   183 PRIAAWFKRLQKLPYYEEAN-GNGA----------------RTFESFIRE 215
             ::|.|  |:|     .|.| |:|.                .|.:|.::|
Human   190 -KLAEW--RMQ-----VELNIGSGLFREAHDRLMQLADWDFSTLDSMVKE 231

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GstE7	NP_611329.1	GST_N_Delta_Epsilon	4..77	CDD:239343	21/72 (29%)
		GST_C_Delta_Epsilon	91..209	CDD:198287	32/150 (21%)
GSTT4	NP_001345593.1	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold	3..78	CDD:469754	21/74 (28%)
		GST_C_Theta	91..217	CDD:198292	32/141 (23%)