DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstE7 and gst1

DIOPT Version :9

Sequence 1:	NP_611329.1	Gene:	GstE7 / 37112	FlyBaseID:	FBgn0063493	Length:	223	Species:	Drosophila melanogaster
Sequence 2:	NP_588298.1	Gene:	gst1 / 2538694	PomBaseID:	SPCC191.09c	Length:	229	Species:	Schizosaccharomyces pombe

Alignment Length:	228	Identity:	68/228 - (29%)
Similarity:	95/228 - (41%)	Gaps:	46/228 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MPKLILYGLEASPPVRAVKLTLAALEVPYEFVEVNTRAKENFSEEFLKKNPQHTVPTLED---DG 62
            |.:..|:.....|....|...|..|::.||...||....|..|.|.|..||...||||.|   :.
pombe     1 MAQFTLWSHAHGPNPWKVVQALKELDLTYETRYVNFSKNEQKSPEHLALNPNGRVPTLIDHHNND 65

  Fly    63 HYIWDSHAIIAYLVSKYGKTDSL-YPKDLLQRAVVDQRLHFES---GVIFANA-----------L 112
            :.||:|.||:.||..||.....: .|:|..:...|.|.|.|::   |:|:..|           :
pombe    66 YTIWESDAILIYLADKYDTERKISLPRDHPEYYKVIQYLFFQASGQGIIWGQAGWFSVYHQELVI 130

  Fly   113 RSITKPLFAGKQTMIPKERY-DAIIEVYDFLEKFLAGNDYVAGNQLTIADFSIISTVSSLEVFV- 175
            .:||              || :.|..|...||..|...||:..|:.||||.|.||..:.||:..
pombe   131 SAIT--------------RYRNEIKRVLGVLEDILKDRDYLVANRFTIADLSFISWNNFLEIIFA 181

  Fly   176 -----------KVDTTK-YPRIAAWFKRLQKLP 196
                       ::|..| :||..:|.:||...|
pombe   182 EGKFSIEEEVPQLDFEKEFPRTYSWHQRLLARP 214

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE7	NP_611329.1	GstA	4..196	CDD:223698	66/223 (30%)
		GST_N_Delta_Epsilon	4..77	CDD:239343	27/75 (36%)
		GST_C_Delta_Epsilon	91..209	CDD:198287	36/134 (27%)
gst1	NP_588298.1	GST_N_Ure2p_like	3..84	CDD:239346	29/80 (36%)
		GstA	5..218	CDD:223698	67/224 (30%)
		GST_C_Ure2p	96..219	CDD:198326	36/133 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	80	1.000	Inparanoid score	I1854
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000035
OrthoInspector	1	1.000	-	-		mtm9258
orthoMCL	1	0.900	-	-		OOG6_100130
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X30
TreeFam	0	0.000	Not matched by this tool.
	8	7.760