DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstE6 and Clic4

DIOPT Version :9

Sequence 1:	NP_611328.1	Gene:	GstE6 / 37111	FlyBaseID:	FBgn0063494	Length:	222	Species:	Drosophila melanogaster
Sequence 2:	NP_114006.1	Gene:	Clic4 / 83718	RGDID:	61857	Length:	253	Species:	Rattus norvegicus

Alignment Length:	185	Identity:	33/185 - (17%)
Similarity:	64/185 - (34%)	Gaps:	64/185 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 PEYLEKNPQHTVPTLEDDGHYIWDSHAIIAYLVSKYADSDALYPKDPLKR-AVVDQRLHFE-SGV 106
            |:||:.:|:|  |.....|..|:...:  ||:.:...:::....:..||. ..:|:.|:.. .|.
  Rat   102 PKYLKLSPKH--PESNTAGMDIFAKFS--AYIKNSRPEANEALERGLLKTLQKLDEYLNSPLPGE 162

  Fly   107 VFANGIRSISKSVLFQGQTKVPKERYDAIIEIYDFVETFLKGQDYIAGNQLTIADFSLVSSVASL 171
            :..|.:..|..|.                             :.::.|:::|:||.:|:..:
  Rat   163 IDENSMEDIKSST-----------------------------RRFLDGDEMTLADCNLLPKL--- 195

  Fly   172 EAFVALDTTKY-----PR--IGAWIKKLEQLPYYEEANGKGVRQLVAIFKKTNFT 219
             ..|.:...||     |:  .|.|                  |.|...:.:..||
  Rat   196 -HIVKVVAKKYRNFDIPKGMTGIW------------------RYLTNAYSRDEFT 231

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE6	NP_611328.1	GstA	4..196	CDD:223698	29/160 (18%)
		GST_N_Delta_Epsilon	4..77	CDD:239343	10/32 (31%)
		GST_C_Delta_Epsilon	91..209	CDD:198287	20/126 (16%)
Clic4	NP_114006.1	Required for insertion into the membrane. /evidence=ECO:0000250	2..101
		GST_N_CLIC	14..104	CDD:239359	1/1 (100%)
		O-ClC	17..252	CDD:129941	33/185 (18%)
		GST_C_family	111..251	CDD:295467	29/176 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166347859
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930