DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstE6 and GDAP1L1

DIOPT Version :9

Sequence 1:	NP_611328.1	Gene:	GstE6 / 37111	FlyBaseID:	FBgn0063494	Length:	222	Species:	Drosophila melanogaster
Sequence 2:	NP_001243666.1	Gene:	GDAP1L1 / 78997	HGNCID:	4213	Length:	386	Species:	Homo sapiens

Alignment Length:	198	Identity:	36/198 - (18%)
Similarity:	71/198 - (35%)	Gaps:	62/198 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 KLTLYGLDPSPPVRAVKLTLAALNLTYEYVNVDIVARAQLSPEYLEKNPQHTVPTLEDDGHYIWD 67
            :||...:.|......::..||  |.|.:.:.:|.....|||..||.|..:.....||.|.
Human   185 ELTTDSMIPKYATAEIRRHLA--NATTDLMKLDHEEEPQLSEPYLSKQKKLMAKILEHDD----- 242

  Fly    68 SHAIIAYLVSKYADSDALYPKDPLKRAVVDQRLHFESGVVFANGIRSISKSVLFQGQTKVPKERY 132
                ::||                                         |.:|  |:..:..::.
Human   243 ----VSYL-----------------------------------------KKIL--GELAMVLDQI 260

  Fly   133 DAIIEIYDFVETFLKGQDYIAGNQLTIADFSLVSSVASLEAFVALDTTKY------PRIGAWIKK 191
            :|.:|.........|.:.::.|...|:||..|.:::..|: |:.| :.||      |.:.::.::
Human   261 EAELEKRKLENEGQKCELWLCGCAFTLADVLLGATLHRLK-FLGL-SKKYWEDGSRPNLQSFFER 323

  Fly   192 LEQ 194
            :::
Human   324 VQR 326

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE6	NP_611328.1	GstA	4..196	CDD:223698	36/197 (18%)
		GST_N_Delta_Epsilon	4..77	CDD:239343	19/72 (26%)
		GST_C_Delta_Epsilon	91..209	CDD:198287	17/110 (15%)
GDAP1L1	NP_001243666.1	GstA	47..333	CDD:223698	36/198 (18%)
		GST_N_GDAP1	47..119	CDD:239350
		GST_C_GDAP1L1	220..330	CDD:198335	28/161 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165154535
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840