DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstE6 and GstD4

DIOPT Version :9

Sequence 1:	NP_611328.1	Gene:	GstE6 / 37111	FlyBaseID:	FBgn0063494	Length:	222	Species:	Drosophila melanogaster
Sequence 2:	NP_524913.1	Gene:	GstD4 / 48337	FlyBaseID:	FBgn0010040	Length:	215	Species:	Drosophila melanogaster

Alignment Length:	200	Identity:	76/200 - (38%)
Similarity:	120/200 - (60%)	Gaps:	5/200 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 RAVKLTLAALNLTYEYVNVDIVARAQLSPEYLEKNPQHTVPTLEDDGHYIWDSHAIIAYLVSKYA 80
            |.:.:...||.|......:.|.....|.||:|:.|||||:|||.|:|..||:|.||..|||.||.
  Fly    13 RTIIMVAKALGLELNKKQLRITEGEHLKPEFLKLNPQHTIPTLVDNGFAIWESRAIAVYLVEKYG 77

  Fly    81 DSDALYPKDPLKRAVVDQRLHFESGVVFANGIRSISKSVLFQGQTKVPKERYDAIIEIYDFVETF 145
            ..|:|:|.||.|||:::|||:|:.|.:. :.........:..||.. ..|.|..:...::|::.|
  Fly    78 KDDSLFPNDPQKRALINQRLYFDMGTLH-DSFMKYYYPFIRTGQLG-NAENYKKVEAAFEFLDIF 140

  Fly   146 LKGQDYIAGNQLTIADFSLVSSVASLEAFVALDTTKYPRIGAWIKKLEQL-PYYEEANGKGVRQL 209
            |:||||:||:|||:||.:::|||::.|. |..|.:|||.:..|....::: |.::| |.||:.|:
  Fly   141 LEGQDYVAGSQLTVADIAILSSVSTFEV-VEFDISKYPNVARWYANAKKITPGWDE-NWKGLLQM 203

  Fly   210 VAIFK 214
            ..:::
  Fly   204 KTMYE 208

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE6	NP_611328.1	GstA	4..196	CDD:223698	70/180 (39%)
		GST_N_Delta_Epsilon	4..77	CDD:239343	26/60 (43%)
		GST_C_Delta_Epsilon	91..209	CDD:198287	41/118 (35%)
GstD4	NP_524913.1	PRK10542	1..184	CDD:182533	70/173 (40%)
		GST_N_Delta_Epsilon	1..74	CDD:239343	26/60 (43%)
		GST_C_Delta_Epsilon	88..204	CDD:198287	42/119 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45460311
Domainoid	1	1.000	54	1.000	Domainoid score	I4138
eggNOG	1	0.900	-	-		E1_COG0625
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	77	1.000	Inparanoid score	I2398
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1231780at2759
OrthoFinder	1	1.000	-	-		FOG0000035
OrthoInspector	1	1.000	-	-		mtm975
orthoMCL	1	0.900	-	-		OOG6_100130
Panther	1	1.100	-	-	P	PTHR43969
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X30
	11	10.800