DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstE6 and gfzf

DIOPT Version :9

Sequence 1:	NP_611328.1	Gene:	GstE6 / 37111	FlyBaseID:	FBgn0063494	Length:	222	Species:	Drosophila melanogaster
Sequence 2:	NP_001014610.1	Gene:	gfzf / 40858	FlyBaseID:	FBgn0250732	Length:	1045	Species:	Drosophila melanogaster

Alignment Length:	215	Identity:	81/215 - (37%)
Similarity:	123/215 - (57%)	Gaps:	14/215 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LTLYGLDPSPPVRAVKLTLAALNLTYEYVNVDIVARAQLSPEYLEKNPQHTVPTLEDDGHYIWDS 68
            :.||.:...||..||::||.||::.|:.:|||..|....|.||.:.|||..:|.|:|||.|:.:|
  Fly   812 MKLYAVSDGPPSLAVRMTLKALDIQYQLINVDFCAMEHRSEEYSKMNPQKEIPVLDDDGFYLSES 876

  Fly    69 HAIIAYLVSKYADSDALYPKDPLKRAVVDQRLHFESGVVFANGIRSISKSVLFQGQTKVP---KE 130
            .||:.||..|||....|||:|...|||::|||.|..|..:| .|.:.|.:.:|....:.|   |:
  Fly   877 IAIMQYLCDKYAPDSTLYPQDVNVRAVINQRLCFNMGFYYA-PISAHSMAPIFFDYKRTPMSLKK 940

  Fly   131 RYDAIIEIYDFVETFLK--GQDYIAGNQLTIADFSLVSSVASLEAFVALDTTKYPRIGAWIK--K 191
            ..:|:    |..||:|:  |..|.||..:|||||:|:|:...||| :..|..::..:..|.:  |
  Fly   941 VQNAL----DVFETYLQRLGTKYAAGENITIADFALISATICLEA-INFDLHQFTLVNKWYETFK 1000

  Fly   192 LEQLPYYEEANGKGVRQLVA 211
            :|....:|.|| .|::::.|
  Fly  1001 VEYPQLWEIAN-SGMQEISA 1019

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE6	NP_611328.1	GstA	4..196	CDD:223698	76/198 (38%)
		GST_N_Delta_Epsilon	4..77	CDD:239343	32/72 (44%)
		GST_C_Delta_Epsilon	91..209	CDD:198287	41/124 (33%)
gfzf	NP_001014610.1	FLYWCH	18..87	CDD:282369
		FLYWCH	162..229	CDD:282369
		FLYWCH	365..432	CDD:282369
		FLYWCH	597..663	CDD:282369
		Thioredoxin_like	811..886	CDD:294274	32/73 (44%)
		GstA	812..1000	CDD:223698	74/193 (38%)
		GST_C_Delta_Epsilon	900..1017	CDD:198287	41/123 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	54	1.000	Domainoid score	I643
eggNOG	1	0.900	-	-		E1_COG0625
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1231780at2759
OrthoFinder	1	1.000	-	-		FOG0000035
OrthoInspector	1	1.000	-	-		mtm975
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR43969
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X30
	8	7.920