DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstE6 and gstt1b

DIOPT Version :9

Sequence 1:	NP_611328.1	Gene:	GstE6 / 37111	FlyBaseID:	FBgn0063494	Length:	222	Species:	Drosophila melanogaster
Sequence 2:	NP_956878.1	Gene:	gstt1b / 393556	ZFINID:	ZDB-GENE-040426-1491	Length:	242	Species:	Danio rerio

Alignment Length:	186	Identity:	51/186 - (27%)
Similarity:	94/186 - (50%)	Gaps:	11/186 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 SPPVRAVKLTLAALNLTYEYVNVDIVARAQLSPEYLEKNPQHTVPTLEDDGHYIWDSHAIIAYLV 76
            |.|.|:|.:.....|:.::|..:.:....|...|:.:.||....||::|....:.:|.||:.||.
Zfish    11 SQPCRSVYIFAKKNNIQFDYKKISLFEGYQYGEEFGKINPLRKFPTIKDGDFCLAESVAIMIYLA 75

  Fly    77 SKYADSDALYPKDPLKRAVVDQRLHFESGVVFANGIRSISKSVLFQG--QTKVPKERYDAI---- 135
            .|:...|..:|.|..|||.|::.|.::...:..:|.:.|...:|...  ..:||||:.:..
Zfish    76 DKFHTPDHWFPADLQKRARVNEYLSWQHTSIRMHGAKIIWFKILIPEVLGAEVPKEKMENAEENL 140

  Fly   136 -IEIYDFVETFLKGQDYIAGNQLTIADFSLVSSVASLEAFVA-LDT-TKYPRIGAW 188
             :.:..|.:.||:.:.:|.|:|:::||  ||:.|..::.|.| :|. ...|::.||
Zfish   141 NVALQLFQDKFLQDKPFIVGDQISLAD--LVAIVEIMQPFAAGMDVFENRPKLKAW 194

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE6	NP_611328.1	GstA	4..196	CDD:223698	51/186 (27%)
		GST_N_Delta_Epsilon	4..77	CDD:239343	18/64 (28%)
		GST_C_Delta_Epsilon	91..209	CDD:198287	29/107 (27%)
gstt1b	NP_956878.1	GstA	1..199	CDD:223698	51/186 (27%)
		GST_N_Theta	3..78	CDD:239348	18/66 (27%)
		GST_C_Theta	91..217	CDD:198292	29/106 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	58	1.000	Domainoid score	I10727
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1231780at2759
OrthoFinder	1	1.000	-	-		FOG0000035
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100130
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X30
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.720