DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment GstE6 and GSTZ1

DIOPT Version :9

Sequence 1:	NP_611328.1	Gene:	GstE6 / 37111	FlyBaseID:	FBgn0063494	Length:	222	Species:	Drosophila melanogaster
Sequence 2:	NP_001350632.1	Gene:	GSTZ1 / 2954	HGNCID:	4643	Length:	217	Species:	Homo sapiens

Alignment Length:	188	Identity:	63/188 - (33%)
Similarity:	97/188 - (51%)	Gaps:	13/188 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 VKLTLAALNLTYEYVNVDIV--ARAQLSPEYLEKNPQHTVPTLEDDGHYIWDSHAIIAYLVSKYA 80
            |::.||...:.||.|.::::  ...|.|.::...||...||||:.||..|..|.|||.|| .:..
Human    21 VRIALALKGIDYETVPINLIKDGGQQFSKDFQALNPMKQVPTLKIDGITIHQSLAIIEYL-EEMR 84

  Fly    81 DSDALYPKDPLKRAVVDQRLHFESGVVFANGIRSISK-SVLFQ-GQTKVPKERYDAIIEIYDFVE 143
            .:..|.|:||.|||.|  |:..:   :.|.||:.:.. |||.| |:........:||...::.:|
Human    85 PTPRLLPQDPKKRASV--RMISD---LIAGGIQPLQNLSVLKQVGEEMQLTWAQNAITCGFNALE 144

  Fly   144 TFLKGQD--YIAGNQLTIADFSLVSSVASLEAFVALDTTKYPRIGAWIKKLEQLPYYE 199
            ..|:...  |..|:::|:||..||..||:.|.| .:|.|.||.|.:..|:|..|..::
Human   145 QILQSTAGIYCVGDEVTMADLCLVPQVANAERF-KVDLTPYPTISSINKRLLVLEAFQ 201

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE6	NP_611328.1	GstA	4..196	CDD:223698	62/183 (34%)
		GST_N_Delta_Epsilon	4..77	CDD:239343	23/60 (38%)
		GST_C_Delta_Epsilon	91..209	CDD:198287	36/113 (32%)
GSTZ1	NP_001350632.1	maiA	8..212	CDD:273527	63/188 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810