DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstE6 and gst1

DIOPT Version :9

Sequence 1:	NP_611328.1	Gene:	GstE6 / 37111	FlyBaseID:	FBgn0063494	Length:	222	Species:	Drosophila melanogaster
Sequence 2:	NP_588298.1	Gene:	gst1 / 2538694	PomBaseID:	SPCC191.09c	Length:	229	Species:	Schizosaccharomyces pombe

Alignment Length:	222	Identity:	69/222 - (31%)
Similarity:	103/222 - (46%)	Gaps:	34/222 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MVKLTL----YGLDPSPPVRAVKLTLAALNLTYEYVNVDIVARAQLSPEYLEKNPQHTVPTLED- 60
            |.:.||    :|.:|...|:|:|    .|:||||...|:.....|.|||:|..||...||||.|
pombe     1 MAQFTLWSHAHGPNPWKVVQALK----ELDLTYETRYVNFSKNEQKSPEHLALNPNGRVPTLIDH 61

  Fly    61 --DGHYIWDSHAIIAYLVSKY-ADSDALYPKDPLKRAVVDQRLHFES---GVVF--ANGIRSISK 117
              :.:.||:|.||:.||..|| .:.....|:|..:...|.|.|.|::   |:::  |.......:
pombe    62 HNNDYTIWESDAILIYLADKYDTERKISLPRDHPEYYKVIQYLFFQASGQGIIWGQAGWFSVYHQ 126

  Fly   118 SVLFQGQTKVPKERYDAIIEIYDFVETFLKGQDYIAGNQLTIADFSLVSSVASLEAFVA------ 176
            .::....|:...|    |..:...:|..||.:||:..|:.||||.|.:|....||...|
pombe   127 ELVISAITRYRNE----IKRVLGVLEDILKDRDYLVANRFTIADLSFISWNNFLEIIFAEGKFSI 187

  Fly   177 ------LDTTK-YPRIGAWIKKLEQLP 196
                  ||..| :||..:|.::|...|
pombe   188 EEEVPQLDFEKEFPRTYSWHQRLLARP 214

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE6	NP_611328.1	GstA	4..196	CDD:223698	67/217 (31%)
		GST_N_Delta_Epsilon	4..77	CDD:239343	32/79 (41%)
		GST_C_Delta_Epsilon	91..209	CDD:198287	32/124 (26%)
gst1	NP_588298.1	GST_N_Ure2p_like	3..84	CDD:239346	34/84 (40%)
		GstA	5..218	CDD:223698	68/218 (31%)
		GST_C_Ure2p	96..219	CDD:198326	32/123 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	80	1.000	Inparanoid score	I1854
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000035
OrthoInspector	1	1.000	-	-		mtm9258
orthoMCL	1	0.900	-	-		OOG6_100130
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R16830
SonicParanoid	1	1.000	-	-		X30
TreeFam	0	0.000	Not matched by this tool.
	9	8.790