DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstE6 and Clic6

DIOPT Version :9

Sequence 1:	NP_611328.1	Gene:	GstE6 / 37111	FlyBaseID:	FBgn0063494	Length:	222	Species:	Drosophila melanogaster
Sequence 2:	NP_766057.1	Gene:	Clic6 / 209195	MGIID:	2146607	Length:	596	Species:	Mus musculus

Alignment Length:	143	Identity:	27/143 - (18%)
Similarity:	58/143 - (40%)	Gaps:	40/143 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 LNLTYEYVNVDIVARAQLSPEYLEKNPQHTVPTLEDDGHYIWDSHAIIAYLVSKYADSDALYPKD 89
            :|...|::...:|     .|.|.:...||  |.....|:.::...:  |::.:...|::.:|.|
Mouse   432 VNKIEEFLEEKLV-----PPRYPKLGTQH--PESNSAGNDVFAKFS--AFIKNTKKDANEIYEK- 486

  Fly    90 PLKRAVVDQRLHFESGVVFANGIRSISK--SVLFQGQTKVPKERYDAIIEIYDFVETFLKGQDYI 152
                                |.:|::.|  |.|   .:.:|.|     |:.....:..:..:.::
Mouse   487 --------------------NLLRALKKLDSYL---NSPLPDE-----IDADSSEDVTVSQRKFL 523

  Fly   153 AGNQLTIADFSLV 165
            .|::||:||.:|:
Mouse   524 DGDELTLADCNLL 536

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE6	NP_611328.1	GstA	4..196	CDD:223698	27/143 (19%)
		GST_N_Delta_Epsilon	4..77	CDD:239343	10/51 (20%)
		GST_C_Delta_Epsilon	91..209	CDD:198287	14/77 (18%)
Clic6	NP_766057.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..360
		PHA02664	<69..167	CDD:177447
		GST_N_CLIC	360..448	CDD:239359	4/20 (20%)
		O-ClC	363..596	CDD:129941	27/143 (19%)
		GST_C_CLIC6	455..594	CDD:198334	21/115 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167844592
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930