DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstE5 and CAM1

DIOPT Version :9

Sequence 1:	NP_611327.1	Gene:	GstE5 / 37110	FlyBaseID:	FBgn0063495	Length:	222	Species:	Drosophila melanogaster
Sequence 2:	NP_015277.1	Gene:	CAM1 / 856059	SGDID:	S000005969	Length:	415	Species:	Saccharomyces cerevisiae

Alignment Length:	204	Identity:	45/204 - (22%)
Similarity:	83/204 - (40%)	Gaps:	31/204 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 PSPPVRAVKLTLAALQLPYEFVNVNISGQEQLSEEYLKKNPEHTVPTLEDDGNY-IWDSHAIIAY 74
            |...|:|:||            :|.:...:..:|::.:..|...||.......| :.::.||..|
Yeast    17 PRGLVKALKL------------DVKVVTPDAAAEQFARDFPLKKVPAFVGPKGYKLTEAMAINYY 69

  Fly    75 LVSKYADSDALYPR------DLLQRAVV---DQRLHFETGVVFANGIKAITKPLFFNGLNRIPKE 130
            || |.:..|.:..:      ||..:|.:   ....:.:..:..||.|..:.....:|  .:....
Yeast    70 LV-KLSQDDKMKTQLLGADDDLNAQAQIIRWQSLANSDLCIQIANTIVPLKGGAPYN--KKSVDS 131

  Fly   131 RYDAIVEIYDFVETFLAGHDYIAGDQLTIADFSLISSIT----SLVAFVEIDRLKYPRIIEWVRR 191
            ..||:.:|.|..|..|..:.|:|.:.:::||....|..|    ||  |....|.::|.|:.|...
Yeast   132 AMDAVDKIVDIFENRLKNYTYLATENISLADLVAASIFTRYFESL--FGTEWRAQHPAIVRWFNT 194

  Fly   192 LEKLPYYEE 200
            :...|:.::
Yeast   195 VRASPFLKD 203

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE5	NP_611327.1	GstA	4..196	CDD:223698	44/198 (22%)
		Thioredoxin_like	4..77	CDD:294274	15/66 (23%)
		GST_C_Delta_Epsilon	91..209	CDD:198287	25/117 (21%)
CAM1	NP_015277.1	GST_N_EF1Bgamma	4..73	CDD:239342	16/68 (24%)
		GST_C_EF1Bgamma_like	92..214	CDD:198290	25/116 (22%)
		EF1G	255..359	CDD:395522
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157345097
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740