DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstE5 and GstD10

DIOPT Version :9

Sequence 1:	NP_611327.1	Gene:	GstE5 / 37110	FlyBaseID:	FBgn0063495	Length:	222	Species:	Drosophila melanogaster
Sequence 2:	NP_001287302.1	Gene:	GstD10 / 59240	FlyBaseID:	FBgn0042206	Length:	210	Species:	Drosophila melanogaster

Alignment Length:	208	Identity:	71/208 - (34%)
Similarity:	118/208 - (56%)	Gaps:	8/208 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LTLYGVNPSPPVRAVKLTLAALQLPYEFVN-VNISGQEQLSEEYLKKNPEHTVPTLEDDGNYIWD 67
            :.||....|.|.|:|.:|..||.:.::... :|...:||.:.||||.||:||:|||.|.|..:|:
  Fly     1 MDLYYRPGSAPCRSVLMTAKALGVEFDKKTIINTRAREQFTPEYLKINPQHTIPTLHDHGFALWE 65

  Fly    68 SHAIIAYLVSKYADSDALYPRDLLQRAVVDQRLHFETGVVFANGIKAITKPLFFNGLNRIPKERY 132
            |.||:.|||.||...|.|:|:|:.::|:::|||:|:.|.::.:..:.....:|..  ....:|.|
  Fly    66 SRAIMVYLVEKYGKDDKLFPKDVQKQALINQRLYFDMGTLYKSFSEYYYPQIFLK--KPANEENY 128

  Fly   133 DAIVEIYDFVETFLAGHDYIAGDQLTIADFSLISSITSL-VAFVEIDRLKYPRIIEWVRRLEKL- 195
            ..|...::|:.|||.|..|.||...::||.:.::::::. ||..:..|  |..:..|....:||
  Fly   129 KKIEVAFEFLNTFLEGQTYSAGGDYSLADIAFLATVSTFDVAGFDFKR--YANVARWYENAKKLT 191

  Fly   196 PYYEEANAKGARE 208
            |.:|| |..|.:|
  Fly   192 PGWEE-NWAGCQE 203

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE5	NP_611327.1	GstA	4..196	CDD:223698	65/194 (34%)
		Thioredoxin_like	4..77	CDD:294274	31/73 (42%)
		GST_C_Delta_Epsilon	91..209	CDD:198287	33/120 (28%)
GstD10	NP_001287302.1	GST_N_Delta_Epsilon	1..75	CDD:239343	31/73 (42%)
		PLN02473	3..196	CDD:166114	66/196 (34%)
		GST_C_Delta_Epsilon	89..205	CDD:198287	33/120 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45460283
Domainoid	1	1.000	54	1.000	Domainoid score	I4138
eggNOG	1	0.900	-	-		E1_COG0625
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	77	1.000	Inparanoid score	I2398
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1231780at2759
OrthoFinder	1	1.000	-	-		FOG0000035
OrthoInspector	1	1.000	-	-		mtm975
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR43969
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X30
	10	9.900