Protein Alignment GstE5 and GDAP1

DIOPT Version :10

• Sequence 1: NP_611327.1
• Gene: GstE5 / 37110
• FlyBaseID: FBgn0063495
• Length: 222
• Species: Drosophila melanogaster
• Sequence 2: NP_061845.2
• Gene: GDAP1 / 54332
• HGNCID: 15968
• Length: 358
• Species: Homo sapiens
• Alignment Length: 291
• Identity: 62/291 - (21%)
• Similarity: 94/291 - (32%)
• Gaps: 99/291 - (34%)

  Fly     2 VKLTLYGVNPSPPVRAVKLTLAALQLPYEFVNVNISGQEQLSEEYLKKNPEHTVPTLEDDGNYIW 66
            |||.||....|...:.|:|.:|...|..|..:|::...|.....:::.|....||.|....|.|.
Human    24 VKLILYHWTHSFSSQKVRLVIAEKALKCEEHDVSLPLSEHNEPWFMRLNSTGEVPVLIHGENIIC 88

  Fly    67 DSHAIIAYLVSKYAD----------SDALYPRDLLQRAVVDQR----------LHFETGV----- 106
            ::..||.||...:.|          ....|||....|.::|..          ||.|..|
Human    89 EATQIIDYLEQTFLDERTPRLMPDKESMYYPRVQHYRELLDSLPMDAYTHGCILHPELTVDSMIP 153

  Fly   107 ------------------------------VFANGIKAITKPLFFNGLNRIPKERYDAIVEIYDF 141
                                          .:....|.:...|..:...:..|:..|.:.::.|.
Human   154 AYATTRIRSQIGNTESELKKLAEENPDLQEAYIAKQKRLKSKLLDHDNVKYLKKILDELEKVLDQ 218

  Fly   142 VETFLAGHD----------YIAGDQLTIADFSLISSITSLVAFVEIDRLKYPRIIEWVRR----- 191
            |||.|...:          ::.|:..|:||.||.         |.:.|||:   :.:.||
Human   219 VETELQRRNEETPEEGQQPWLCGESFTLADVSLA---------VTLHRLKF---LGFARRNWGNG 271

  Fly   192 ----LEKLPYYEEANAKGARELETILKSTNF 218
                ||  .|||.           :||...|
Human   272 KRPNLE--TYYER-----------VLKRKTF 289

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GstE5	NP_611327.1	GstA	4..210	CDD:440390	57/279 (20%)
GDAP1	NP_061845.2	GST_N_GDAP1	26..98	CDD:239350	20/71 (28%)
		GST_C_GDAP1	179..289	CDD:198336	28/134 (21%)
		Required for mitochondrial localization	320..358