DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstE5 and GstD7

DIOPT Version :9

Sequence 1:	NP_611327.1	Gene:	GstE5 / 37110	FlyBaseID:	FBgn0063495	Length:	222	Species:	Drosophila melanogaster
Sequence 2:	NP_525114.1	Gene:	GstD7 / 48340	FlyBaseID:	FBgn0010043	Length:	224	Species:	Drosophila melanogaster

Alignment Length:	224	Identity:	78/224 - (34%)
Similarity:	124/224 - (55%)	Gaps:	20/224 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MVKLTLYGVNPSPPVRAVKLTLAALQLPYEFVNVNISGQEQLSEEYLKKNPEHTVPTLEDDGNYI 65
            |..|.||....:|..||:::...||.|......:|....:||..|:::.||:||:|||.|:|..|
  Fly     1 MPNLDLYNFPMAPASRAIQMVAKALGLELNSKLINTMEGDQLKPEFVRINPQHTIPTLVDNGFVI 65

  Fly    66 WDSHAIIAYLVSKYADSDA-LYPRDLLQRAVVDQRLHFETGVVFANGIKAITKPLFFNGLNRIPK 129
            |:|.||..|||.||...|: |||.|..:||:::|||:|:.|.::    .|:||..|.  :.|..|
  Fly    66 WESRAIAVYLVEKYGKPDSPLYPNDPQKRALINQRLYFDMGTLY----DALTKYFFL--IFRTGK 124

  Fly   130 ----ERYDAIVEIYDFVETFLAGHDYIAGDQLTIADFSLISSITSLVAFVEIDRLKYPRIIEWVR 190
                |..|.:...:.|:.|||.|.|::||.|||:||..::::: |.|.:...|..|:|.:..|::
  Fly   125 FGDQEALDKVNSAFGFLNTFLEGQDFVAGSQLTVADIVILATV-STVEWFSFDLSKFPNVERWLK 188

  Fly   191 RLEKL-PYYEEANAKGARELETILKSTNF 218
            ...|: |.:|:       .||::.:...|
  Fly   189 NAPKVTPGWEQ-------NLESLQQGKKF 210

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE5	NP_611327.1	GstA	4..196	CDD:223698	72/197 (37%)
		Thioredoxin_like	4..77	CDD:294274	29/72 (40%)
		GST_C_Delta_Epsilon	91..209	CDD:198287	37/122 (30%)
GstD7	NP_525114.1	GST_N_Delta_Epsilon	4..77	CDD:239343	29/72 (40%)
		GstA	6..188	CDD:223698	70/188 (37%)
		GST_C_Delta_Epsilon	92..206	CDD:198287	39/127 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45460335
Domainoid	1	1.000	54	1.000	Domainoid score	I4138
eggNOG	1	0.900	-	-		E1_COG0625
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	77	1.000	Inparanoid score	I2398
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1231780at2759
OrthoFinder	1	1.000	-	-		FOG0000035
OrthoInspector	1	1.000	-	-		mtm975
orthoMCL	1	0.900	-	-		OOG6_100130
Panther	1	1.100	-	-	P	PTHR43969
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X30
	11	10.800