DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstE5 and eEF1gamma

DIOPT Version :9

Sequence 1:	NP_611327.1	Gene:	GstE5 / 37110	FlyBaseID:	FBgn0063495	Length:	222	Species:	Drosophila melanogaster
Sequence 2:	NP_001189308.1	Gene:	eEF1gamma / 44791	FlyBaseID:	FBgn0029176	Length:	431	Species:	Drosophila melanogaster

Alignment Length:	190	Identity:	54/190 - (28%)
Similarity:	86/190 - (45%)	Gaps:	34/190 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MVKLTLYGVNPSPPVRAVKLTLAALQLPYEFVNVNIS-----GQEQLSEEYLKKNPEHTVPTLED 60
            |||.|||....:  .||.|..:||   .|....|.::     |:...|.|:|||.|...||..|.
  Fly     1 MVKGTLYTYPEN--FRAYKALIAA---QYSGAQVKVADNFKFGETNKSAEFLKKFPGGKVPAFET 60

  Fly    61 -DGNYIWDSHAIIAYLVSKYADSDALYPRDLLQRAVVDQRLHF-ETGVVFAN--------GIKAI 115
             :|.|:.:|:| ||||::.........|   ..:|.|.|.:.| :..:|.|:        ||...
  Fly    61 AEGQYLSESNA-IAYLLANEQLRGGKCP---FVQAQVQQWISFADNEIVPASCAWVFPLLGILPQ 121

  Fly   116 TKPLFFNGLNRIPKERYDAIVEIYDFVETFLAGHDYIAGDQLTIADFSLISSITSLVAFV 175
            .|       |...|:..:|:::   .:...|....::||:::|:||..:.||:..|..:|
  Fly   122 QK-------NSTAKQEAEAVLQ---QLNQKLQDATFLAGERITLADIVVFSSLLHLYEYV 171

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE5	NP_611327.1	GstA	4..196	CDD:223698	51/187 (27%)
		Thioredoxin_like	4..77	CDD:294274	28/78 (36%)
		GST_C_Delta_Epsilon	91..209	CDD:198287	22/94 (23%)
eEF1gamma	NP_001189308.1	GST_N_EF1Bgamma	4..79	CDD:239342	28/80 (35%)
		GstA	5..187	CDD:223698	51/186 (27%)
		GST_C_EF1Bgamma_like	90..209	CDD:198290	22/92 (24%)
		EF1G	271..376	CDD:279041
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45459954
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740