DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstE5 and GstE12

DIOPT Version :9

Sequence 1:	NP_611327.1	Gene:	GstE5 / 37110	FlyBaseID:	FBgn0063495	Length:	222	Species:	Drosophila melanogaster
Sequence 2:	NP_001246500.1	Gene:	GstE12 / 37960	FlyBaseID:	FBgn0027590	Length:	223	Species:	Drosophila melanogaster

Alignment Length:	216	Identity:	91/216 - (42%)
Similarity:	133/216 - (61%)	Gaps:	2/216 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MVKLTLYGVNPSPPVRAVKLTLAALQLPYEFVNVNISGQEQLSEEYLKKNPEHTVPTLEDDGNYI 65
            |.|..||....|||.|||.||..|:.|..|...:|:...|.|:.|:||.||:||:|||.|....|
  Fly     1 MSKPALYYATLSPPSRAVLLTAKAIGLDLELRPINLLKGEHLTPEFLKLNPQHTIPTLIDGEATI 65

  Fly    66 WDSHAIIAYLVSKYADSD-ALYPRDLLQRAVVDQRLHFETGVVFANGIKAITKPLFFNGLNRIPK 129
            .|||||.||||.||...: .|||::|:|||.||.|||.::|.:||. ::.:.:|:.:.|......
  Fly    66 IDSHAICAYLVEKYGQKEQQLYPKELVQRANVDARLHLDSGHLFAR-LRFLYEPILYYGSTDCSI 129

  Fly   130 ERYDAIVEIYDFVETFLAGHDYIAGDQLTIADFSLISSITSLVAFVEIDRLKYPRIIEWVRRLEK 194
            ::...|.:.::.:|.||....|:.|..||||||..::::||:.....||..|:|::..|::||.:
  Fly   130 DKIAYIQKCWEILEGFLKDQPYLCGSDLTIADFCAVATVTSVNDTAPIDEFKFPKMHAWLKRLAE 194

  Fly   195 LPYYEEANAKGARELETILKS 215
            ||||:|.|..||.||::|.|:
  Fly   195 LPYYQEVNGDGADELKSIFKA 215

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE5	NP_611327.1	GstA	4..196	CDD:223698	77/192 (40%)
		Thioredoxin_like	4..77	CDD:294274	36/72 (50%)
		GST_C_Delta_Epsilon	91..209	CDD:198287	42/117 (36%)
GstE12	NP_001246500.1	GST_N_Delta_Epsilon	4..77	CDD:239343	36/72 (50%)
		GstA	6..201	CDD:223698	81/195 (42%)
		GST_C_Delta_Epsilon	92..210	CDD:198287	43/118 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468015
Domainoid	1	1.000	54	1.000	Domainoid score	I4138
eggNOG	1	0.900	-	-		E1_COG0625
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	77	1.000	Inparanoid score	I2398
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D118089at33392
OrthoFinder	1	1.000	-	-		FOG0000035
OrthoInspector	1	1.000	-	-		mtm975
orthoMCL	1	0.900	-	-		OOG6_100130
Panther	1	1.100	-	-	P	PTHR43969
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X30
	11	10.800